Accutane and Varicose vein - a phase IV clinical study of FDA data

Summary:

Varicose vein is reported as a side effect among people who take Accutane (isotretinoin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Varicose vein when taking Accutane. It is created by eHealthMe based on reports of 33,410 people who have side effects when taking Accutane from the FDA, and is updated regularly.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

What is Varicose vein?

Varicose vein (veins that have become enlarged and tortuous) is found to be associated with 692 drugs and 737 conditions by eHealthMe. Check the latest studies of Varicose vein.

On Jul, 07, 2026

33,410 people reported to have side effects when taking Accutane.
Among them, 39 people (0.12%) have Varicose vein.

Among these 39 people:

How long have people been on Accutane when they have Varicose vein? *

What is the gender of people who have Varicose vein when taking Accutane? *

female: 76.32 %
male: 23.68 %

What is the age of people who have Varicose vein when taking Accutane? *

What are other drugs people take besides Accutane? *

What are other side effects people have besides Varicose vein? *

High Blood Cholesterol: 27 people, 69.23%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 27 people, 69.23%
Kidney Stones: 26 people, 66.67%
Drug Ineffective: 26 people, 66.67%
Joint Pain: 26 people, 66.67%
Renal Disorder (kidney disease): 26 people, 66.67%
Drowsiness: 25 people, 64.10%
Pain: 25 people, 64.10%
High Blood Pressure: 24 people, 61.54%
Vein Disorder: 24 people, 61.54%

What are the existing conditions these people have? *

Pain: 25 people, 64.10%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 23 people, 58.97%
Kidney Stones: 23 people, 58.97%
Ear Discomfort: 23 people, 58.97%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 13 people, 33.33%
Sinobronchitis (long lasting paranasal sinusitis with repeated bronchitis): 4 people, 10.26%
Infection: 4 people, 10.26%
Diarrhea: 4 people, 10.26%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 10.26%
Osteoporosis (bones weak and more likely to break): 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Accutane and have Varicose vein?

- Check whether Varicose vein is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Accutane:

Accutane (35,221 reports)

Varicose vein treatments and more:

Varicose vein (8,020 reports)

Browse all side effects of Accutane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Varicose vein:

Varicose vein (692 drugs)

Browse all the conditions that are associated with Varicose vein:

Varicose vein (737 conditions)

Related publications that referenced our studies

Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Accutane) and Accutane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.