Acetylsalicylic acid and Bundle branch block - a phase IV clinical study of FDA data

Summary:

Bundle branch block is reported as a side effect among people who take Acetylsalicylic acid (aspirin), especially for people who are male, 60+ old, also take Clopidogrel, and have Hypocholesterolaemia.

The phase IV clinical study analyzes which people have Bundle branch block when taking Acetylsalicylic acid. It is created by eHealthMe based on reports of 119,623 people who have side effects when taking Acetylsalicylic acid from the FDA, and is updated regularly.

What is Acetylsalicylic acid?

Acetylsalicylic acid has active ingredients of aspirin. It is often used in high blood pressure. eHealthMe is studying from 119,766 Acetylsalicylic acid users. Check the latest studies of Acetylsalicylic acid.

What is Bundle branch block?

Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat) is found to be associated with 231 drugs and 397 conditions by eHealthMe. Check the latest studies of Bundle branch block.

On Jul, 25, 2026

119,623 people reported to have side effects when taking Acetylsalicylic acid.
Among them, 24 people (0.02%) have Bundle branch block.

Could Acetylsalicylic acid cause Bundle branch block?

Among these 24 people:

What is the gender of people who have Bundle branch block when taking Acetylsalicylic acid? *

female: 17.39 %
male: 82.61 %

What is the age of people who have Bundle branch block when taking Acetylsalicylic acid? *

What are other drugs people take besides Acetylsalicylic acid? *

What are other side effects people have besides Bundle branch block? *

Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 4 people, 16.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 16.67%
Weight Decreased: 3 people, 12.50%
Myopathy Toxic (a muscular disease in which the muscle fibres do not function due to toxin): 3 people, 12.50%
Hoarseness Or Changing Voice: 3 people, 12.50%
Atrioventricular Block Complete (heart block complete): 3 people, 12.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 12.50%
Swallowing Difficulty: 3 people, 12.50%
Conduction Disorder (serious disorder of the heart not responses proper to impulses): 3 people, 12.50%
Ventricular Extrasystoles (premature cardiac contraction): 3 people, 12.50%

What are the existing conditions these people have? *

Parkinson's Disease: 5 people, 20.83%
Hypocholesterolaemia (presence of abnormally small amounts of cholesterol in the circulating blood): 5 people, 20.83%
Dyslipidaemia (abnormal amount of lipids): 4 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 8.33%
Blockage Of Leg Arteries: 1 person, 4.17%
Cardiac Failure: 1 person, 4.17%
Cardioversion: 1 person, 4.17%
Cough: 1 person, 4.17%
Coughing Up Blood: 1 person, 4.17%
Cutaneous Lupus Erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Acetylsalicylic acid and have Bundle branch block?

- Check whether Bundle branch block is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetylsalicylic acid:

Acetylsalicylic acid (119,766 reports)

Browse all side effects of Acetylsalicylic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bundle branch block:

Bundle branch block (231 drugs)

Browse all the conditions that are associated with Bundle branch block:

Bundle branch block (397 conditions)

Related publications that referenced our studies

Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on aspirin (the active ingredients of Acetylsalicylic acid) and Acetylsalicylic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.