Aciphex and Irritable bowel syndrome - a phase IV clinical study of FDA data

Summary:

Irritable bowel syndrome is reported as a side effect among people who take Aciphex (rabeprazole sodium), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Xanax, and have High blood pressure.

The phase IV clinical study analyzes which people have Irritable bowel syndrome when taking Aciphex. It is created by eHealthMe based on reports of 24,594 people who have side effects when taking Aciphex from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Irritable bowel syndrome?

Irritable bowel syndrome is found to be associated with 1,317 drugs and 2,122 conditions by eHealthMe. Check the latest studies of Irritable bowel syndrome.

On Jul, 17, 2026

24,594 people reported to have side effects when taking Aciphex.
Among them, 131 people (0.53%) have Irritable bowel syndrome.

Could Aciphex cause Irritable bowel syndrome?

Among these 131 people:

How long have people been on Aciphex when they have Irritable bowel syndrome? *

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What is the gender of people who have Irritable bowel syndrome when taking Aciphex? *

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What is the age of people who have Irritable bowel syndrome when taking Aciphex? *

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* Approximation only. Some reports may have incomplete information.

Do you take Aciphex and have Irritable bowel syndrome?

- Check whether Irritable bowel syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aciphex:

Aciphex (25,301 reports)

Irritable bowel syndrome treatments and more:

Irritable bowel syndrome (49,237 reports)

How severe was Irritable bowel syndrome and when was it recovered:

Irritable bowel syndrome in Aciphex

Expand to all the drugs that have ingredients of rabeprazole sodium:

Irritable bowel syndrome and drugs with ingredients of rabeprazole sodium (206 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (1,317 drugs)

Browse all the conditions that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (2,122 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Aciphex) and Aciphex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.