Actemra and Thyroid cancer - a phase IV clinical study of FDA data

Summary:

Thyroid cancer is reported as a side effect among people who take Actemra (tocilizumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Arava, and have Osteoarthritis.

The phase IV clinical study analyzes which people have Thyroid cancer when taking Actemra. It is created by eHealthMe based on reports of 102,551 people who have side effects when taking Actemra from the FDA, and is updated regularly.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.

What is Thyroid cancer?

Thyroid cancer is found to be associated with 586 drugs and 844 conditions by eHealthMe. Check the latest studies of Thyroid cancer.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

102,551 people reported to have side effects when taking Actemra.
Among them, 67 people (0.07%) have Thyroid cancer.

Could Actemra cause Thyroid cancer?

Among these 67 people:

How long have people been on Actemra when they have Thyroid cancer? *

  • < 1 month: 28.57 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 28.57 %
  • 1 - 2 years: 28.57 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Thyroid cancer when taking Actemra? *

  • female: 24.62 %
  • male: 75.38 %

What is the age of people who have Thyroid cancer when taking Actemra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.45 %
  • 40-49: 1.72 %
  • 50-59: 6.9 %
  • 60+: 87.93 %

What are other drugs people take besides Actemra? *

  1. Arava: 51 people, 76.12%
  2. Orencia: 47 people, 70.15%
  3. Xeljanz: 28 people, 41.79%
  4. Plaquenil: 25 people, 37.31%
  5. Enbrel: 25 people, 37.31%
  6. Methotrexate: 5 people, 7.46%
  7. Synthroid: 5 people, 7.46%
  8. Sumatriptan: 1 person, 1.49%
  9. Levothyroxine Sodium: 1 person, 1.49%
  10. Allopurinol: 1 person, 1.49%

What are other side effects people have besides Thyroid cancer? *

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 53 people, 79.10%
  2. Abdominal Discomfort: 49 people, 73.13%
  3. Nodule (a growth of abnormal tissue): 49 people, 73.13%
  4. Nausea (feeling of having an urge to vomit): 49 people, 73.13%
  5. Malaise (a feeling of general discomfort or uneasiness): 47 people, 70.15%
  6. Eye Disorder: 47 people, 70.15%
  7. Rectal Haemorrhage (bleeding from anus): 47 people, 70.15%
  8. Drug Ineffective: 47 people, 70.15%
  9. Herpes Zoster: 47 people, 70.15%
  10. Limb Discomfort (discomfort in leg): 46 people, 68.66%

What are the existing conditions these people have? *

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 13.43%
  2. High Blood Pressure: 2 people, 2.99%
  3. Vasculitis (inflammation of a blood vessel or blood vessels): 1 person, 1.49%
  4. Thyroid Diseases: 1 person, 1.49%
  5. Takayasu's Arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body): 1 person, 1.49%
  6. Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 1.49%
  7. Pain: 1 person, 1.49%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 1.49%
  9. Castleman's Disease (a disease of lymph nodes and related tissues): 1 person, 1.49%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 1.49%

* Approximation only. Some reports may have incomplete information.

Do you take Actemra and have Thyroid cancer?

- Check whether Thyroid cancer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actemra:

Thyroid cancer treatments and more:

How severe was Thyroid cancer and when was it recovered:

Expand to all the drugs that have ingredients of tocilizumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actemra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid cancer:

Browse all the conditions that are associated with Thyroid cancer:


How the study uses the data?

The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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