Acth and Injection site swelling - a phase IV clinical study of FDA data

Summary:

Injection site swelling is reported as a side effect among people who take Acth (corticotropin), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Aspirin, and have Systemic lupus erythematosus.

The phase IV clinical study analyzes which people have Injection site swelling when taking Acth. It is created by eHealthMe based on reports of 5,384 people who have side effects when taking Acth from the FDA, and is updated regularly.

What is Acth?

Acth has active ingredients of corticotropin. eHealthMe is studying from 5,402 Acth users. Check the latest studies of Acth.

What is Injection site swelling?

Injection site swelling is found to be associated with 1,058 drugs and 1,115 conditions by eHealthMe. Check the latest studies of Injection site swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

5,384 people reported to have side effects when taking Acth.
Among them, 43 people (0.8%) have Injection site swelling.

Could Acth cause Injection site swelling?

Among these 43 people:

How long have people been on Acth when they have Injection site swelling? *

What is the gender of people who have Injection site swelling when taking Acth? *

female: 90.48 %
male: 9.52 %

What is the age of people who have Injection site swelling when taking Acth? *

What are other drugs people take besides Acth? *

What are other side effects people have besides Injection site swelling? *

Injection Site Erythema (redness at injection site): 15 people, 34.88%
Injection Site Pruritus (severe itching at injection site): 14 people, 32.56%
Injection Site Bruising: 12 people, 27.91%
Injection Site Pain: 11 people, 25.58%
Injection Site Discoloration: 8 people, 18.60%
Injection Site Reaction: 7 people, 16.28%
Rashes (redness): 6 people, 13.95%
Injection Site Discomfort: 6 people, 13.95%
Diarrhea: 5 people, 11.63%
Injection Site Warmth: 5 people, 11.63%

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 6 people, 13.95%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 5 people, 11.63%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 11.63%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 9.30%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 4 people, 9.30%
Haematuria (presence of blood in urine): 3 people, 6.98%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.98%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 4.65%
Pulmonary Sarcoidosis (growth of tiny collections of inflammatory cells in lungs): 2 people, 4.65%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Acth and have Injection site swelling?

- Check whether Injection site swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acth:

Acth (5,402 reports)

Browse all side effects of Acth:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site swelling:

Injection site swelling (1,058 drugs)

Browse all the conditions that are associated with Injection site swelling:

Injection site swelling (1,115 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on corticotropin (the active ingredients of Acth) and Acth (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.