Acthar and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Acthar (corticotropin), especially for people who are male, 0-1 old, have been taking the drug for < 1 month also take Lasix, and have Infantile spasms.

The phase IV clinical study analyzes which people have Irritability when taking Acthar. It is created by eHealthMe based on reports of 4,932 people who have side effects when taking Acthar from the FDA, and is updated regularly.

What is Acthar?

Acthar has active ingredients of corticotropin. eHealthMe is studying from 4,948 Acthar users. Check the latest studies of Acthar.

What is Irritability?

Irritability is found to be associated with 1,700 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 12, 2026

4,932 people reported to have side effects when taking Acthar.
Among them, 73 people (1.48%) have Irritability.

Among these 73 people:

How long have people been on Acthar when they have Irritability? *

What is the gender of people who have Irritability when taking Acthar? *

female: 45.21 %
male: 54.79 %

What is the age of people who have Irritability when taking Acthar? *

What are other drugs people take besides Acthar? *

What are other side effects people have besides Irritability? *

Weight Increased: 17 people, 23.29%
Insomnia (sleeplessness): 17 people, 23.29%
Drowsiness: 17 people, 23.29%
Fatigue (feeling of tiredness): 14 people, 19.18%
Memory Loss: 12 people, 16.44%
Blood Glucose Increased: 11 people, 15.07%
High Blood Pressure: 11 people, 15.07%
Dyspnea (difficult or laboured breathing): 11 people, 15.07%
Peripheral Swelling: 10 people, 13.70%
Feeling Abnormal: 10 people, 13.70%

What are the existing conditions these people have? *

Infantile Spasms: 23 people, 31.51%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 13.70%
Blood Glucose Increased: 6 people, 8.22%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 6 people, 8.22%
Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 8.22%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 5 people, 6.85%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.11%
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli): 3 people, 4.11%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 4.11%
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 2 people, 2.74%

* Approximation only. Some reports may have incomplete information.

Do you take Acthar and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acthar:

Acthar (4,948 reports)

Irritability treatments and more:

Irritability (71,614 reports)

Browse all side effects of Acthar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,700 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on corticotropin (the active ingredients of Acthar) and Acthar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.