Actigall and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Actigall (ursodiol), especially for people who are male, 60+ old, also take Zofran, and have Hypotension.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Actigall. It is created by eHealthMe based on reports of 2,122 people who have side effects when taking Actigall from the FDA, and is updated regularly.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,468 drugs and 2,014 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Jan, 27, 2026

2,122 people reported to have side effects when taking Actigall.
Among them, 17 people (0.8%) have Hepatic function abnormal.

Could Actigall cause Hepatic function abnormal?

Among these 17 people:

What is the gender of people who have Hepatic function abnormal when taking Actigall? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Hepatic function abnormal when taking Actigall? *

What are other drugs people take besides Actigall? *

What are other side effects people have besides Hepatic function abnormal? *

Ascites (accumulation of fluid in the abdominal cavity): 7 people, 41.18%
Skin Ulcer: 5 people, 29.41%
Hepatomegaly (abnormal enlargement of the liver): 4 people, 23.53%
Pleural Effusion (water on the lungs): 4 people, 23.53%
Rashes (redness): 4 people, 23.53%
Abdominal Distension: 4 people, 23.53%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 17.65%
Bronchopulmonary Dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type): 3 people, 17.65%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 17.65%
Generalised Oedema (swelling all over the body): 3 people, 17.65%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 3 people, 17.65%
Itching: 3 people, 17.65%
Hypotension (abnormally low blood pressure): 3 people, 17.65%
Thrombocytopenia (decrease of platelets in blood): 2 people, 11.76%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 11.76%
Skin Ulcer: 2 people, 11.76%
Iron Metabolism Disorder: 2 people, 11.76%
Cough: 2 people, 11.76%
Acute Myeloid Leukaemia (In Remission): 2 people, 11.76%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Actigall and have Hepatic function abnormal?

- Check whether Hepatic function abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actigall:

Actigall (2,162 reports)

Browse all side effects of Actigall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic function abnormal:

Hepatic function abnormal (1,468 drugs)

Browse all the conditions that are associated with Hepatic function abnormal:

Hepatic function abnormal (2,014 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol (the active ingredients of Actigall) and Actigall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.