Actigall and Sinusitis - a phase IV clinical study of FDA data

Summary:

Sinusitis is reported as a side effect among people who take Actigall (ursodiol), especially for people who are female, 60+ old, also take Vitamin D3, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Sinusitis when taking Actigall. It is created by eHealthMe based on reports of 2,122 people who have side effects when taking Actigall from the FDA, and is updated regularly.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

What is Sinusitis?

Sinusitis (inflammation of sinus) is found to be associated with 2,399 drugs and 2,727 conditions by eHealthMe. Check the latest studies of Sinusitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

2,122 people reported to have side effects when taking Actigall.
Among them, 16 people (0.75%) have Sinusitis.

Among these 16 people:

What is the gender of people who have Sinusitis when taking Actigall? *

female: 75 %
male: 25 %

What is the age of people who have Sinusitis when taking Actigall? *

What are other drugs people take besides Actigall? *

What are other side effects people have besides Sinusitis? *

Diarrhea: 3 people, 18.75%
Nausea (feeling of having an urge to vomit): 3 people, 18.75%
Nausea And Vomiting: 3 people, 18.75%
Anaemia (lack of blood): 2 people, 12.50%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 2 people, 12.50%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 2 people, 12.50%
Headache (pain in head): 2 people, 12.50%
Pleural Effusion (water on the lungs): 2 people, 12.50%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 6.25%
Hepatic Steatosis (fatty liver disease): 1 person, 6.25%

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 5 people, 31.25%
Immunodeficiency Common Variable: 3 people, 18.75%
Hepatitis C: 2 people, 12.50%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 6.25%
Dyspnea (difficult or laboured breathing): 1 person, 6.25%
Anaemia (lack of blood): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Actigall and have Sinusitis?

- Check whether Sinusitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actigall:

Actigall (2,162 reports)

Sinusitis treatments and more:

Sinusitis (153,485 reports)

Browse all side effects of Actigall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinusitis:

Sinusitis (2,399 drugs)

Browse all the conditions that are associated with Sinusitis:

Sinusitis (2,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol (the active ingredients of Actigall) and Actigall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.