Actiq and Tooth injury - a phase IV clinical study of FDA data

Summary:

Tooth injury is reported as a side effect among people who take Actiq (fentanyl citrate), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Ms Contin, and have Breakthrough pain.

The phase IV clinical study analyzes which people have Tooth injury when taking Actiq. It is created by eHealthMe based on reports of 27,560 people who have side effects when taking Actiq from the FDA, and is updated regularly.

What is Actiq?

Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.

What is Tooth injury?

Tooth injury is found to be associated with 437 drugs and 411 conditions by eHealthMe. Check the latest studies of Tooth injury.



On Jul, 25, 2026

27,560 people reported to have side effects when taking Actiq.
Among them, 12 people (0.04%) have Tooth injury.

Could Actiq cause Tooth injury?

Among these 12 people:

How long have people been on Actiq when they have Tooth injury? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 66.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 33.33 %

What is the gender of people who have Tooth injury when taking Actiq? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Tooth injury when taking Actiq? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 20 %
  • 40-49: 80 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Actiq? *

  1. Zanaflex: 2 people, 16.67%
  2. Valium: 2 people, 16.67%
  3. Ultram: 2 people, 16.67%
  4. Tenormin: 2 people, 16.67%
  5. Robaxin: 2 people, 16.67%
  6. Prozac: 2 people, 16.67%
  7. Oxycontin: 2 people, 16.67%
  8. Nuvigil: 2 people, 16.67%
  9. Neurontin: 2 people, 16.67%
  10. Ms Contin: 2 people, 16.67%

What are other side effects people have besides Tooth injury? *

  1. Dental Caries: 7 people, 58.33%
  2. Tooth Fracture: 5 people, 41.67%
  3. Toothaches (tooth pain): 3 people, 25.00%
  4. Incoherent (talking in a confused and unclear way): 2 people, 16.67%
  5. Infection: 2 people, 16.67%
  6. Depression: 2 people, 16.67%
  7. Dermatitis Contact (skin reaction (dermatitis) resulting from exposure to allergens): 2 people, 16.67%
  8. Emotional Distress: 2 people, 16.67%
  9. Feeding Disorder (when children refuse to eat certain food groups): 2 people, 16.67%
  10. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Spinal Pain (pain in spine): 2 people, 16.67%
  2. Nerve Injury: 2 people, 16.67%
  3. Muscle Spasms (muscle contraction): 2 people, 16.67%
  4. Drowsiness: 2 people, 16.67%
  5. Cardiac Disorder: 2 people, 16.67%
  6. Breakthrough Pain: 2 people, 16.67%
  7. Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Actiq and have Tooth injury?

- Check whether Tooth injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actiq:

Tooth injury treatments and more:

How severe was Tooth injury and when was it recovered:

Expand to all the drugs that have ingredients of fentanyl citrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actiq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tooth injury:

Browse all the conditions that are associated with Tooth injury:


How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Actiq) and Actiq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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