Actonel and Pulmonary oedema aggravated - a phase IV clinical study of FDA data
Summary:
Pulmonary oedema aggravated is found among people who take Actonel, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Actonel and have Pulmonary oedema aggravated. It is created by eHealthMe based on reports of 28,020 people who have side effects when taking Actonel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
28,020 people reported to have side effects when taking Actonel.
Among them, 100 people (0.36%) have Pulmonary oedema aggravated.
What is Actonel?
Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 28,458 Actonel users for its effectiveness, alternative drugs and more.
What is Pulmonary oedema aggravated?
Pulmonary oedema aggravated (aggravated fluid accumulation in the lungs) is found to be associated with 1,639 drugs and 501 conditions by eHealthMe.
Number of Actonel and Pulmonary oedema aggravated reports submitted per year:

Time on Actonel when people have Pulmonary oedema aggravated *:
- < 1 month: 20 %
- 1 - 6 months: 60 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 10 %
- 5 - 10 years: 10 %
- 10+ years: 0.0 %
Gender of people who have Pulmonary oedema aggravated when taking Actonel *:
- female: 76 %
- male: 24 %
Age of people who have Pulmonary oedema aggravated when taking Actonel *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 2.44 %
- 50-59: 19.51 %
- 60+: 78.05 %
Common drugs people take besides Actonel *:
- Spiriva: 17 people, 17.00%
- Lasix: 15 people, 15.00%
- Actemra: 13 people, 13.00%
- Plavix: 12 people, 12.00%
- Prednisone: 12 people, 12.00%
- Prevacid: 12 people, 12.00%
- Folic Acid: 12 people, 12.00%
- Methotrexate: 11 people, 11.00%
- Rituxan: 10 people, 10.00%
- Premarin: 10 people, 10.00%
Common side effects people have besides Pulmonary oedema aggravated *:
- Pneumonia: 29 people, 29.00%
- Breathing Difficulty: 28 people, 28.00%
- Oedema Peripheral (superficial swelling): 26 people, 26.00%
- Pleural Effusion (water on the lungs): 25 people, 25.00%
- Pain: 25 people, 25.00%
- Nausea And Vomiting: 25 people, 25.00%
- Hypotension (abnormally low blood pressure): 22 people, 22.00%
- Weakness: 22 people, 22.00%
- Fever: 22 people, 22.00%
- Joint Pain: 21 people, 21.00%
Common conditions people have *:
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 32 people, 32.00%
- Gastritis (inflammation of stomach): 6 people, 6.00%
- High Blood Pressure: 6 people, 6.00%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 6.00%
- Sinusitis (inflammation of sinus): 5 people, 5.00%
- Cardiac Failure Congestive: 5 people, 5.00%
- Pneumonia: 5 people, 5.00%
- Pituitary Tumor: 4 people, 4.00%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 4.00%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 4.00%
* Approximation only. Some reports may have incomplete information.
Do you take Actonel and have Pulmonary oedema aggravated?
Check whether Pulmonary oedema aggravated is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Related studies
How severe was Pulmonary oedema aggravated and when was it recovered:
Expand to all the drugs that have ingredients of risedronate sodium:
Alternative drugs to, pros and cons of Actonel:
- Actonel (28,458 reports)
Common Actonel side effects:
- Joint pain: 3,009 reports
- Pain: 2,624 reports
- Drug ineffective: 2,398 reports
- Fatigue (feeling of tiredness): 2,225 reports
- Diarrhea: 2,122 reports
Browse all side effects of Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zPulmonary oedema aggravated treatments and more:
- Pulmonary oedema aggravated (12 reports)
COVID vaccines that are related to Pulmonary oedema aggravated:
- Pulmonary oedema aggravated in Moderna COVID Vaccine
- Pulmonary oedema aggravated in Pfizer BioNTech Covid Vaccine
- Pulmonary oedema aggravated in Johnson and Johnson Covid Vaccine
Common drugs associated with Pulmonary oedema aggravated:
- Furosemide: 3,532 reports
- Aspirin: 3,093 reports
- Lasix: 3,037 reports
- Prednisone: 2,672 reports
- Amlodipine: 1,895 reports
- Omeprazole: 1,767 reports
- Humira: 1,706 reports
- Metformin: 1,651 reports
- Methotrexate: 1,580 reports
- Lisinopril: 1,381 reports
All the drugs that are associated with Pulmonary oedema aggravated:
- Pulmonary oedema aggravated (1,639 drugs)
Common conditions associated with Pulmonary oedema aggravated:
- High blood pressure: 2,562 reports
- Rheumatoid arthritis: 2,255 reports
- Multiple myeloma: 1,463 reports
- Pain: 1,419 reports
- Depression: 981 reports
- Atrial fibrillation/flutter: 806 reports
- Multiple sclerosis: 777 reports
All the conditions that are associated with Pulmonary oedema aggravated:
- Pulmonary oedema aggravated (501 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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