Actos and Conjunctival haemorrhage - a phase IV clinical study of FDA data

Summary:

Conjunctival haemorrhage is reported as a side effect among people who take Actos (pioglitazone hydrochloride), especially for people who are female, 60+ old, also take Revlimid, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Conjunctival haemorrhage when taking Actos. It is created by eHealthMe based on reports of 49,087 people who have side effects when taking Actos from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Conjunctival haemorrhage?

Conjunctival haemorrhage (bleeding underneath the conjunctiva) is found to be associated with 509 drugs and 561 conditions by eHealthMe. Check the latest studies of Conjunctival haemorrhage.

On Aug, 09, 2026

49,087 people reported to have side effects when taking Actos.
Among them, 28 people (0.06%) have Conjunctival haemorrhage.

Could Actos cause Conjunctival haemorrhage?

Among these 28 people:

What is the gender of people who have Conjunctival haemorrhage when taking Actos? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Conjunctival haemorrhage when taking Actos? *

What are other drugs people take besides Actos? *

What are other side effects people have besides Conjunctival haemorrhage? *

Neuropathy Peripheral (surface nerve damage): 20 people, 71.43%
Muscle Spasms (muscle contraction): 20 people, 71.43%
Pain: 20 people, 71.43%
Constipation: 20 people, 71.43%
Osteonecrosis Of Jaw (death of bone of jaw): 20 people, 71.43%
Exostosis (formation of new bone on the surface of a bone): 20 people, 71.43%
Chest Pain: 20 people, 71.43%
Facet Joint Syndrome (problem with movement of the facet joints of the spine): 20 people, 71.43%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 20 people, 71.43%
Kidney Stones: 20 people, 71.43%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 35.71%
High Blood Cholesterol: 4 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.29%
Osteoporosis (bones weak and more likely to break): 3 people, 10.71%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 7.14%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 3.57%
Prostate Cancer: 1 person, 3.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.57%
High Density Lipoprotein Decreased: 1 person, 3.57%
High Blood Pressure: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Actos and have Conjunctival haemorrhage?

- Check whether Conjunctival haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actos:

Actos (49,754 reports)

Browse all side effects of Actos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Conjunctival haemorrhage:

Conjunctival haemorrhage (509 drugs)

Browse all the conditions that are associated with Conjunctival haemorrhage:

Conjunctival haemorrhage (561 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Actos) and Actos (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.