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Actrapid and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Actrapid (insulin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Apixaban, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Actrapid. It is created by eHealthMe based on reports of 4,843 people who have side effects when taking Actrapid from the FDA, and is updated regularly.

What is Actrapid?

Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,935 drugs and 2,859 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Aug, 13, 2026

4,843 people reported to have side effects when taking Actrapid.
Among them, 19 people (0.39%) have Anaphylaxis.

Could Actrapid cause Anaphylaxis?

Among these 19 people:

How long have people been on Actrapid when they have Anaphylaxis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Anaphylaxis when taking Actrapid? *

  • female: 22.22 %
  • male: 77.78 %

What is the age of people who have Anaphylaxis when taking Actrapid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.88 %
  • 20-29: 17.65 %
  • 30-39: 0.0 %
  • 40-49: 17.65 %
  • 50-59: 11.76 %
  • 60+: 47.06 %

What are other drugs people take besides Actrapid? *

  1. Oxaliplatin: 4 people, 21.05%
  2. Gemcitabine Hydrochloride: 4 people, 21.05%
  3. Torsemide: 4 people, 21.05%
  4. Apixaban: 4 people, 21.05%
  5. Lipitor: 3 people, 15.79%
  6. Amicar: 3 people, 15.79%
  7. Aspirin: 3 people, 15.79%
  8. Coenzyme Q10: 3 people, 15.79%
  9. Refludan: 3 people, 15.79%
  10. Ranitidine: 3 people, 15.79%

What are other side effects people have besides Anaphylaxis? *

  1. Hypotension (abnormally low blood pressure): 5 people, 26.32%
  2. Abdominal Distension: 3 people, 15.79%
  3. Blindness: 3 people, 15.79%
  4. Skin Exfoliation (removal of the oldest dead skin cells): 3 people, 15.79%
  5. Dermatitis Bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid): 3 people, 15.79%
  6. Oedema Peripheral (superficial swelling): 3 people, 15.79%
  7. Optic Ischaemic Neuropathy (optic nerve damage due to lack of blood supply): 3 people, 15.79%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 15.79%
  9. Cardiac Arrest: 2 people, 10.53%
  10. Rashes (redness): 2 people, 10.53%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 4 people, 21.05%
  2. Rickets (softening of bones): 4 people, 21.05%
  3. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 21.05%
  4. Oedema (fluid collection in tissue): 4 people, 21.05%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 21.05%
  6. Pneumonia: 2 people, 10.53%
  7. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 10.53%
  8. Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 10.53%
  9. Cardiac Failure Chronic: 2 people, 10.53%
  10. Sedation: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Actrapid and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actrapid:

Anaphylaxis treatments and more:

How severe was Anaphylaxis and when was it recovered:

Expand to all the drugs that have ingredients of insulin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actrapid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Browse all the conditions that are associated with Anaphylaxis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on insulin (the active ingredients of Actrapid) and Actrapid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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