Acular and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Acular (ketorolac tromethamine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lovenox, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Fever when taking Acular. It is created by eHealthMe based on reports of 1,109 people who have side effects when taking Acular from the FDA, and is updated regularly.

What is Acular?

Acular has active ingredients of ketorolac tromethamine. eHealthMe is studying from 1,125 Acular users. Check the latest studies of Acular.

What is Fever?

Fever is found to be associated with 3,493 drugs and 6,196 conditions by eHealthMe. Check the latest studies of Fever.



On Jul, 15, 2026

1,109 people reported to have side effects when taking Acular.
Among them, 22 people (1.98%) have Fever.

Could Acular cause Fever?

Among these 22 people:

How long have people been on Acular when they have Fever? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fever when taking Acular? *

  • female: 68.18 %
  • male: 31.82 %

What is the age of people who have Fever when taking Acular? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5 %
  • 50-59: 20 %
  • 60+: 75 %

What are other drugs people take besides Acular? *

  1. Lovenox: 7 people, 31.82%
  2. Digoxin: 6 people, 27.27%
  3. Prednisone: 5 people, 22.73%
  4. Aspirin: 5 people, 22.73%
  5. Zithromax: 5 people, 22.73%
  6. Acetaminophen: 5 people, 22.73%
  7. Methotrexate: 5 people, 22.73%
  8. Levaquin: 5 people, 22.73%
  9. Gabapentin: 5 people, 22.73%
  10. Zolpidem: 4 people, 18.18%

What are other side effects people have besides Fever? *

  1. Nausea And Vomiting: 9 people, 40.91%
  2. Nausea (feeling of having an urge to vomit): 9 people, 40.91%
  3. Acute Kidney Failure: 7 people, 31.82%
  4. Anaemia (lack of blood): 6 people, 27.27%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 27.27%
  6. Cellulitis (infection under the skin): 6 people, 27.27%
  7. Pain: 6 people, 27.27%
  8. Headache (pain in head): 5 people, 22.73%
  9. Fall: 5 people, 22.73%
  10. Head Injury: 5 people, 22.73%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 2 people, 9.09%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.55%
  3. Osteoporosis (bones weak and more likely to break): 1 person, 4.55%
  4. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 4.55%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.55%
  6. Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 1 person, 4.55%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.55%
  8. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Acular and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acular:

Fever treatments and more:

  • Fever (498,666 reports)

How severe was Fever and when was it recovered:

Expand to all the drugs that have ingredients of ketorolac tromethamine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acular:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Browse all the conditions that are associated with Fever:

  • Fever (6,196 conditions)

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ketorolac tromethamine (the active ingredients of Acular) and Acular (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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