Acular and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Acular (ketorolac tromethamine), especially for people who are male, 60+ old, also take Toprol-Xl, and have Diabetes.

The phase IV clinical study analyzes which people have Stroke when taking Acular. It is created by eHealthMe based on reports of 1,109 people who have side effects when taking Acular from the FDA, and is updated regularly.

What is Acular?

Acular has active ingredients of ketorolac tromethamine. eHealthMe is studying from 1,125 Acular users. Check the latest studies of Acular.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,363 drugs and 3,019 conditions by eHealthMe. Check the latest studies of Stroke.



On Feb, 08, 2026

1,109 people reported to have side effects when taking Acular.
Among them, 21 people (1.89%) have Stroke.

Could Acular cause Stroke?

Among these 21 people:

What is the gender of people who have Stroke when taking Acular? *

  • female: 38.1 %
  • male: 61.9 %

What is the age of people who have Stroke when taking Acular? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 27.78 %
  • 60+: 72.22 %

What are other drugs people take besides Acular? *

  1. Prilosec: 7 people, 33.33%
  2. Toprol-Xl: 7 people, 33.33%
  3. Acetaminophen And Hydrocodone Bitartrate: 6 people, 28.57%
  4. Coumadin: 6 people, 28.57%
  5. Nexium: 6 people, 28.57%
  6. Lortab: 6 people, 28.57%
  7. Cephalexin: 6 people, 28.57%
  8. Claritin: 6 people, 28.57%
  9. Norvasc: 5 people, 23.81%
  10. Nexavar: 5 people, 23.81%

What are other side effects people have besides Stroke? *

  1. Dyspnea (difficult or laboured breathing): 11 people, 52.38%
  2. High Blood Pressure: 10 people, 47.62%
  3. Stress And Anxiety: 9 people, 42.86%
  4. Pleural Effusion (water on the lungs): 8 people, 38.10%
  5. Depression: 8 people, 38.10%
  6. Fatigue (feeling of tiredness): 7 people, 33.33%
  7. Injury: 7 people, 33.33%
  8. Visual Acuity Reduced (reduced clearness of vision): 7 people, 33.33%
  9. Constipation: 6 people, 28.57%
  10. Confusional State: 6 people, 28.57%

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 14.29%
  2. Diabetes: 3 people, 14.29%
  3. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 9.52%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.52%
  5. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 1 person, 4.76%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.76%
  7. Pain: 1 person, 4.76%
  8. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 1 person, 4.76%
  9. Joint Pain: 1 person, 4.76%
  10. Heart Rate Irregular: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Acular and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acular:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of ketorolac tromethamine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acular:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:


How the study uses the data?

The study uses data from the FDA. It is based on ketorolac tromethamine (the active ingredients of Acular) and Acular (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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