Acyclovir and Atrioventricular block second degree - a phase IV clinical study of FDA data

Summary:

Atrioventricular block second degree is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are female, 30-39 old, also take Allopurinol, and have Hepatosplenic candidiasis.

The phase IV clinical study analyzes which people have Atrioventricular block second degree when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Atrioventricular block second degree?

Atrioventricular block second degree (heart block second degree) is found to be associated with 373 drugs and 819 conditions by eHealthMe. Check the latest studies of Atrioventricular block second degree.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 43 people (0.08%) have Atrioventricular block second degree.

Could Acyclovir cause Atrioventricular block second degree?

Among these 43 people:

What is the gender of people who have Atrioventricular block second degree when taking Acyclovir? *

female: 82.93 %
male: 17.07 %

What is the age of people who have Atrioventricular block second degree when taking Acyclovir? *

What are other drugs people take besides Acyclovir? *

Allopurinol: 35 people, 81.40%
Etoposide: 29 people, 67.44%
Noxafil: 28 people, 65.12%
Cytarabine: 28 people, 65.12%
Pantoprazole Sodium: 24 people, 55.81%
Ondansetron: 19 people, 44.19%
Dexamethasone: 16 people, 37.21%
Omeprazole: 8 people, 18.60%
Ondansetron Hydrochloride: 6 people, 13.95%
Prednisone: 6 people, 13.95%

What are other side effects people have besides Atrioventricular block second degree? *

Sinoatrial Block: 28 people, 65.12%
Bradycardia (abnormally slow heart action): 25 people, 58.14%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 20 people, 46.51%
Nodal Arrhythmia (an irregular heart beat originating from within the atrioventricular node): 14 people, 32.56%
Arrhythmias (irregular heartbeat): 12 people, 27.91%
Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 11 people, 25.58%
Bradyarrhythmia (heart slowness): 11 people, 25.58%
Fatigue (feeling of tiredness): 7 people, 16.28%
Hypokalemia (low potassium): 3 people, 6.98%
Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 3 people, 6.98%

What are the existing conditions these people have? *

Hepatosplenic Candidiasis (fungal infection in liver and spleen): 28 people, 65.12%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 13.95%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 13.95%
High Blood Pressure: 6 people, 13.95%
Multiple Myeloma (cancer of the plasma cells): 2 people, 4.65%
Oedema (fluid collection in tissue): 1 person, 2.33%
Neuralgia (pain in one or more nerves): 1 person, 2.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.33%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 2.33%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Atrioventricular block second degree?

- Check whether Atrioventricular block second degree is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrioventricular block second degree:

Atrioventricular block second degree (373 drugs)

Browse all the conditions that are associated with Atrioventricular block second degree:

Atrioventricular block second degree (819 conditions)

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.