Acyclovir and Brain herniation - a phase IV clinical study of FDA data

Summary:

Brain herniation is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Ceftriaxone, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Brain herniation when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Brain herniation?

Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull) is found to be associated with 337 drugs and 975 conditions by eHealthMe. Check the latest studies of Brain herniation.

On Jul, 17, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 37 people (0.07%) have Brain herniation.

Among these 37 people:

How long have people been on Acyclovir when they have Brain herniation? *

What is the gender of people who have Brain herniation when taking Acyclovir? *

female: 21.21 %
male: 78.79 %

What is the age of people who have Brain herniation when taking Acyclovir? *

What are other drugs people take besides Acyclovir? *

What are other side effects people have besides Brain herniation? *

Cerebral Haemorrhage (bleeding within the brain): 17 people, 45.95%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 16 people, 43.24%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 16 people, 43.24%
C-Reactive Protein Increased: 11 people, 29.73%
Pain: 10 people, 27.03%
Drowsiness: 10 people, 27.03%
Endocarditis (inflammation in heart muscle): 8 people, 21.62%
Pulmonary Embolism (blockage of the main artery of the lung): 8 people, 21.62%
Renal Injury (kidney injury): 7 people, 18.92%
Overdose: 7 people, 18.92%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 8 people, 21.62%
Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 7 people, 18.92%
Leukaemia (blood or bone marrow cancer): 4 people, 10.81%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 5.41%
Bone Marrow Conditioning Regimen: 2 people, 5.41%
Infection: 2 people, 5.41%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 2 people, 5.41%
Neuroblastoma (a cancer that forms in your nerve tissue): 2 people, 5.41%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 2.70%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Brain herniation?

- Check whether Brain herniation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain herniation:

Brain herniation (337 drugs)

Browse all the conditions that are associated with Brain herniation:

Brain herniation (975 conditions)

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.