Acyclovir and Enterocolitis - a phase IV clinical study of FDA data

Summary:

Enterocolitis is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Omeprazole, and have Nausea.

The phase IV clinical study analyzes which people have Enterocolitis when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,957 Acyclovir users. Check the latest studies of Acyclovir.

What is Enterocolitis?

Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon) is found to be associated with 738 drugs and 723 conditions by eHealthMe. Check the latest studies of Enterocolitis.



On Sep, 21, 2025

53,484 people reported to have side effects when taking Acyclovir.
Among them, 83 people (0.16%) have Enterocolitis.

Could Acyclovir cause Enterocolitis?

Among these 83 people:

How long have people been on Acyclovir when they have Enterocolitis? *

  • < 1 month: 53.85 %
  • 1 - 6 months: 23.08 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 15.38 %
  • 2 - 5 years: 7.69 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Enterocolitis when taking Acyclovir? *

  • female: 60.27 %
  • male: 39.73 %

What is the age of people who have Enterocolitis when taking Acyclovir? *

  • 0-1: 0.0 %
  • 2-9: 10.61 %
  • 10-19: 9.09 %
  • 20-29: 9.09 %
  • 30-39: 3.03 %
  • 40-49: 1.52 %
  • 50-59: 13.64 %
  • 60+: 53.03 %

What are other drugs people take besides Acyclovir? *

  1. Omeprazole: 33 people, 39.76%
  2. Dexamethasone: 32 people, 38.55%
  3. Acetaminophen: 31 people, 37.35%
  4. Prednisolone: 31 people, 37.35%
  5. Ondansetron: 30 people, 36.14%
  6. Potassium Chloride: 28 people, 33.73%
  7. Sodium Chloride: 26 people, 31.33%
  8. Allopurinol: 26 people, 31.33%
  9. Metoclopramide: 22 people, 26.51%
  10. Oxaliplatin: 21 people, 25.30%

What are other side effects people have besides Enterocolitis? *

  1. Hypokalemia (low potassium): 27 people, 32.53%
  2. Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 20 people, 24.10%
  3. Thrombocytopenia (decrease of platelets in blood): 18 people, 21.69%
  4. Diarrhea: 16 people, 19.28%
  5. Dyspnea (difficult or laboured breathing): 12 people, 14.46%
  6. Anaemia (lack of blood): 12 people, 14.46%
  7. Nausea (feeling of having an urge to vomit): 11 people, 13.25%
  8. Fatigue (feeling of tiredness): 10 people, 12.05%
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 10 people, 12.05%
  10. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 8 people, 9.64%

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 10 people, 12.05%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 9 people, 10.84%
  3. Pain: 9 people, 10.84%
  4. High Blood Cholesterol: 8 people, 9.64%
  5. Diarrhea: 8 people, 9.64%
  6. Skin Blushing/flushing (a sudden reddening of the face, neck): 7 people, 8.43%
  7. Metastases To Bone (cancer spreads to bone): 7 people, 8.43%
  8. Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 6 people, 7.23%
  9. Diffuse Large B-Cell Lymphoma Stage Ii (cancer of b cells, a type of white blood cell-stage ii): 6 people, 7.23%
  10. Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Enterocolitis?

- Check whether Enterocolitis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Enterocolitis treatments and more:

How severe was Enterocolitis and when was it recovered:

Browse all side effects of Acyclovir:

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Browse all the drugs that are associated with Enterocolitis:

Browse all the conditions that are associated with Enterocolitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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