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Acyclovir and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,959 Acyclovir users. Check the latest studies of Acyclovir.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,487 drugs and 2,010 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Nov, 04, 2025

53,484 people reported to have side effects when taking Acyclovir.
Among them, 197 people (0.37%) have Hepatic function abnormal.

Could Acyclovir cause Hepatic function abnormal?

Among these 197 people:

How long have people been on Acyclovir when they have Hepatic function abnormal? *

  • < 1 month: 51.72 %
  • 1 - 6 months: 31.03 %
  • 6 - 12 months: 1.72 %
  • 1 - 2 years: 5.17 %
  • 2 - 5 years: 3.45 %
  • 5 - 10 years: 6.9 %
  • 10+ years: 0.0 %

What is the gender of people who have Hepatic function abnormal when taking Acyclovir? *

  • female: 39.36 %
  • male: 60.64 %

What is the age of people who have Hepatic function abnormal when taking Acyclovir? *

  • 0-1: 1.12 %
  • 2-9: 10.11 %
  • 10-19: 11.8 %
  • 20-29: 5.06 %
  • 30-39: 7.87 %
  • 40-49: 11.8 %
  • 50-59: 19.1 %
  • 60+: 33.15 %

What are other drugs people take besides Acyclovir? *

  1. Methotrexate: 41 people, 20.81%
  2. Fluconazole: 39 people, 19.80%
  3. Acetaminophen: 32 people, 16.24%
  4. Prednisolone: 31 people, 15.74%
  5. Tacrolimus: 31 people, 15.74%
  6. Cyclophosphamide: 30 people, 15.23%
  7. Levofloxacin: 29 people, 14.72%
  8. Methylprednisolone Sodium Succinate: 28 people, 14.21%
  9. Micafungin Sodium: 27 people, 13.71%
  10. Ursodiol: 26 people, 13.20%

What are other side effects people have besides Hepatic function abnormal? *

  1. Fever: 49 people, 24.87%
  2. Thrombocytopenia (decrease of platelets in blood): 34 people, 17.26%
  3. Rashes (redness): 32 people, 16.24%
  4. Anaemia (lack of blood): 30 people, 15.23%
  5. Diarrhea: 29 people, 14.72%
  6. Acute Kidney Failure: 25 people, 12.69%
  7. White Blood Cell Count Decreased: 22 people, 11.17%
  8. Alanine Aminotransferase Increased: 22 people, 11.17%
  9. Febrile Neutropenia (fever with reduced white blood cells): 22 people, 11.17%
  10. Renal Impairment (severely reduced kidney function): 21 people, 10.66%

What are the existing conditions these people have? *

  1. Bone Marrow Conditioning Regimen: 25 people, 12.69%
  2. Multiple Myeloma (cancer of the plasma cells): 22 people, 11.17%
  3. Insomnia (sleeplessness): 12 people, 6.09%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 10 people, 5.08%
  5. Hiv Infection: 10 people, 5.08%
  6. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 5.08%
  7. Pneumonia: 9 people, 4.57%
  8. Pain: 9 people, 4.57%
  9. Constipation: 9 people, 4.57%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 9 people, 4.57%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Hepatic function abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Hepatic function abnormal treatments and more:

How severe was Hepatic function abnormal and when was it recovered:

Expand to all the drugs that have ingredients of acyclovir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Acyclovir side effects:

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hepatic function abnormal:

Browse all the drugs that are associated with Hepatic function abnormal:

Common conditions associated with Hepatic function abnormal:

Browse all the conditions that are associated with Hepatic function abnormal:

Drugs similar to Acyclovir and Hepatic function abnormal :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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