Acyclovir and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Aspirin, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Rickets when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,100 drugs and 1,456 conditions by eHealthMe. Check the latest studies of Rickets.



On Apr, 09, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 48 people (0.09%) have Rickets.

Could Acyclovir cause Rickets?

Among these 48 people:

How long have people been on Acyclovir when they have Rickets? *

  • < 1 month: 20 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 80 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Rickets when taking Acyclovir? *

  • female: 64.44 %
  • male: 35.56 %

What is the age of people who have Rickets when taking Acyclovir? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.78 %
  • 20-29: 2.78 %
  • 30-39: 2.78 %
  • 40-49: 13.89 %
  • 50-59: 38.89 %
  • 60+: 38.89 %

What are other drugs people take besides Acyclovir? *

  1. Aspirin: 11 people, 22.92%
  2. Acetaminophen: 9 people, 18.75%
  3. Omeprazole: 9 people, 18.75%
  4. Ondansetron: 8 people, 16.67%
  5. Hydrochlorothiazide: 8 people, 16.67%
  6. Zometa: 8 people, 16.67%
  7. Vitamin D3: 7 people, 14.58%
  8. Doxycycline: 7 people, 14.58%
  9. Lorazepam: 7 people, 14.58%
  10. Dexamethasone: 7 people, 14.58%

What are other side effects people have besides Rickets? *

  1. Stress And Anxiety: 21 people, 43.75%
  2. Fatigue (feeling of tiredness): 18 people, 37.50%
  3. Pain: 18 people, 37.50%
  4. Osteoporosis (bones weak and more likely to break): 15 people, 31.25%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 14 people, 29.17%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 13 people, 27.08%
  7. Bone Density Decreased: 12 people, 25.00%
  8. Depression: 12 people, 25.00%
  9. Chest Pain: 12 people, 25.00%
  10. Oedema Peripheral (superficial swelling): 10 people, 20.83%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 20.83%
  2. Pain: 7 people, 14.58%
  3. Diabetes: 7 people, 14.58%
  4. High Blood Cholesterol: 7 people, 14.58%
  5. Diarrhea: 6 people, 12.50%
  6. Hiv Infection: 5 people, 10.42%
  7. High Blood Pressure: 4 people, 8.33%
  8. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 6.25%
  9. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 6.25%
  10. Hypersensitivity: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Rickets?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Rickets treatments and more:

How severe was Rickets and when was it recovered:

Expand to all the drugs that have ingredients of acyclovir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Browse all the conditions that are associated with Rickets:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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