Adcal and Rectal prolapse - a phase IV clinical study of FDA data

Summary:

Rectal prolapse is reported as a side effect among people who take Adcal (calcium carbonate), especially for people who are female, also take Prolia, and have High blood pressure.

The phase IV clinical study analyzes which people have Rectal prolapse when taking Adcal. It is created by eHealthMe based on reports of 4,800 people who have side effects when taking Adcal from the FDA, and is updated regularly.

What is Adcal?

Adcal has active ingredients of calcium carbonate. eHealthMe is studying from 4,844 Adcal users. Check the latest studies of Adcal.

What is Rectal prolapse?

Rectal prolapse (falling of rectum from normal place) is found to be associated with 306 drugs and 341 conditions by eHealthMe. Check the latest studies of Rectal prolapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

4,800 people reported to have side effects when taking Adcal.
Among them, 21 people (0.44%) have Rectal prolapse.

Among these 21 people:

What is the gender of people who have Rectal prolapse when taking Adcal? *

female: 100 %
male: 0.0 %

What are other drugs people take besides Adcal? *

Prolia: 21 people, 100.00%
Alendronic Acid: 15 people, 71.43%
Amlodipine: 14 people, 66.67%

What are other side effects people have besides Rectal prolapse? *

Urination - Painful: 21 people, 100.00%
Dyspnea (difficult or laboured breathing): 21 people, 100.00%
Bone Pain: 21 people, 100.00%
Rhinorrhea (watery mucus discharge from the nose): 21 people, 100.00%
Burning Sensation: 21 people, 100.00%
Pain: 21 people, 100.00%
Muscle Spasms (muscle contraction): 21 people, 100.00%
Muscle Aches (muscle pain): 21 people, 100.00%
Joint Pain: 21 people, 100.00%
Constipation: 21 people, 100.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 18 people, 85.71%
High Blood Pressure: 18 people, 85.71%
Muscle Aches (muscle pain): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Adcal and have Rectal prolapse?

- Check whether Rectal prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adcal:

Adcal (4,844 reports)

Rectal prolapse treatments and more:

Rectal prolapse (1,711 reports)

Browse all side effects of Adcal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal prolapse:

Rectal prolapse (306 drugs)

Browse all the conditions that are associated with Rectal prolapse:

Rectal prolapse (341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on calcium carbonate (the active ingredients of Adcal) and Adcal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.