Adderall and Abnormal weight gain - a phase IV clinical study of FDA data

Summary:

Abnormal weight gain is reported as a side effect among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate), especially for people who are male, 10-19 old, have been taking the drug for 2 - 5 years also take Risperdal, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Abnormal weight gain when taking Adderall. It is created by eHealthMe based on reports of 50,493 people who have side effects when taking Adderall from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Abnormal weight gain?

Abnormal weight gain is found to be associated with 257 drugs and 708 conditions by eHealthMe. Check the latest studies of Abnormal weight gain.

On Jul, 10, 2026

50,493 people reported to have side effects when taking Adderall.
Among them, 76 people (0.15%) have Abnormal weight gain.

Could Adderall cause Abnormal weight gain?

Among these 76 people:

How long have people been on Adderall when they have Abnormal weight gain? *

What is the gender of people who have Abnormal weight gain when taking Adderall? *

female: 8 %
male: 92 %

What is the age of people who have Abnormal weight gain when taking Adderall? *

What are other drugs people take besides Adderall? *

What are other side effects people have besides Abnormal weight gain? *

Gynecomastia (enlargement of the gland tissue of the male breast): 66 people, 86.84%
Emotional Distress: 18 people, 23.68%
Galactorrhea (secretion of breast milk in men): 17 people, 22.37%
Hyperprolactinaemia (abnormally high levels of prolactin in the blood): 14 people, 18.42%
Emotional Disorder: 10 people, 13.16%
Tardive Dyskinesia (a disorder that involves involuntary movements): 7 people, 9.21%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 7 people, 9.21%
Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 9.21%
Agitation (state of anxiety or nervous excitement): 5 people, 6.58%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 5 people, 6.58%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 20 people, 26.32%
Aggression: 12 people, 15.79%
Affective Disorder (mental disorder): 10 people, 13.16%
Sleep Disorder: 8 people, 10.53%
Autism (a mental condition, present from early childhood, characterized by difficulty in communicating and forming relationships with other people and in using language and abstract concepts): 6 people, 7.89%
Anger: 5 people, 6.58%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 6.58%
Abnormal Behavior: 4 people, 5.26%
Gilles De La Tourette Syndrome (a condition that causes people to make repeated, quick movements or sounds that they cannot control): 4 people, 5.26%
Oppositional Defiant Disorder (a childhood disorder described by the diagnostic and statistical manual of mental disorders): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and have Abnormal weight gain?

- Check whether Abnormal weight gain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adderall:

Adderall (64,224 reports)

Abnormal weight gain treatments and more:

Abnormal weight gain (17,865 reports)

How severe was Abnormal weight gain and when was it recovered:

Abnormal weight gain in Adderall

Expand to all the drugs that have ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate:

Abnormal weight gain and drugs with ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (68 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal weight gain:

Abnormal weight gain (257 drugs)

Browse all the conditions that are associated with Abnormal weight gain:

Abnormal weight gain (708 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Adderall) and Adderall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.