Adderall and Clonus - a phase IV clinical study of FDA data

Summary:

Clonus is reported as a side effect among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate), especially for people who are female, 40-49 old, also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Clonus when taking Adderall. It is created by eHealthMe based on reports of 50,493 people who have side effects when taking Adderall from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Clonus?

Clonus (series of involuntary, rhythmic, muscular contractions and relaxations) is found to be associated with 299 drugs and 560 conditions by eHealthMe. Check the latest studies of Clonus.

On Jul, 14, 2026

50,493 people reported to have side effects when taking Adderall.
Among them, 11 people (0.02%) have Clonus.

Among these 11 people:

What is the gender of people who have Clonus when taking Adderall? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Clonus when taking Adderall? *

What are other drugs people take besides Adderall? *

What are other side effects people have besides Clonus? *

Weakness: 5 people, 45.45%
Hyperreflexia (overactive or over responsive reflexes): 4 people, 36.36%
Gait Disturbance: 4 people, 36.36%
Fatigue (feeling of tiredness): 4 people, 36.36%
Blood Pressure Fluctuation: 4 people, 36.36%
Muscle Rigidity (muscle stiffness): 4 people, 36.36%
Agitation (state of anxiety or nervous excitement): 4 people, 36.36%
Unresponsive To Stimuli: 3 people, 27.27%
Dry Mouth: 3 people, 27.27%
Drug Ineffective: 3 people, 27.27%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 45.45%
Fatigue (feeling of tiredness): 4 people, 36.36%
Gait Disturbance: 3 people, 27.27%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
Vision Blurred: 1 person, 9.09%
Uveitis (inflammation of the uvea): 1 person, 9.09%
Stress And Anxiety: 1 person, 9.09%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 9.09%
Pain: 1 person, 9.09%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and have Clonus?

- Check whether Clonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adderall:

Adderall (64,224 reports)

Clonus treatments and more:

Clonus (3,236 reports)

How severe was Clonus and when was it recovered:

Clonus in Adderall

Expand to all the drugs that have ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate:

Clonus and drugs with ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (23 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clonus:

Clonus (299 drugs)

Browse all the conditions that are associated with Clonus:

Clonus (560 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Adderall) and Adderall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.