Adderall and Hyperprolactinaemia - a phase IV clinical study of FDA data

Summary:

Hyperprolactinaemia is reported as a side effect among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate), especially for people who are male, 30-39 old, have been taking the drug for 1 - 6 months also take Risperdal, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Hyperprolactinaemia when taking Adderall. It is created by eHealthMe based on reports of 50,493 people who have side effects when taking Adderall from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,204 Adderall users. Check the latest studies of Adderall.

What is Hyperprolactinaemia?

Hyperprolactinaemia (abnormally high levels of prolactin in the blood) is found to be associated with 269 drugs and 387 conditions by eHealthMe. Check the latest studies of Hyperprolactinaemia.

On Aug, 05, 2025

50,493 people reported to have side effects when taking Adderall.
Among them, 46 people (0.09%) have Hyperprolactinaemia.

Could Adderall cause Hyperprolactinaemia?

Among these 46 people:

How long have people been on Adderall when they have Hyperprolactinaemia? *

What is the gender of people who have Hyperprolactinaemia when taking Adderall? *

female: 23.91 %
male: 76.09 %

What is the age of people who have Hyperprolactinaemia when taking Adderall? *

What are other drugs people take besides Adderall? *

What are other side effects people have besides Hyperprolactinaemia? *

Gynecomastia (enlargement of the gland tissue of the male breast): 33 people, 71.74%
Galactorrhea (secretion of breast milk in men): 22 people, 47.83%
Weight Loss: 17 people, 36.96%
Abnormal Weight Gain: 14 people, 30.43%
Weight Increased: 8 people, 17.39%
Emotional Distress: 8 people, 17.39%
Haemangioma Of Liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver): 6 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.04%
Contrast Media Allergy (reaction associated with the use of intravenous contrast material during radiology): 5 people, 10.87%
Menstrual Disorder (disease of menstrual cycle): 5 people, 10.87%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 9 people, 19.57%
Affective Disorder (mental disorder): 8 people, 17.39%
Oppositional Defiant Disorder (a childhood disorder described by the diagnostic and statistical manual of mental disorders): 7 people, 15.22%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 15.22%
Aggression: 6 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.04%
Stress And Anxiety: 5 people, 10.87%
Hypersensitivity: 5 people, 10.87%
Pain: 5 people, 10.87%
Neuropathy Peripheral (surface nerve damage): 5 people, 10.87%

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and have Hyperprolactinaemia?

- Check whether Hyperprolactinaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adderall:

Adderall (64,204 reports)

Hyperprolactinaemia treatments and more:

Hyperprolactinaemia (10,936 reports)

How severe was Hyperprolactinaemia and when was it recovered:

Hyperprolactinaemia in Adderall

Expand to all the drugs that have ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate:

Hyperprolactinaemia and drugs with ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (41 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperprolactinaemia:

Hyperprolactinaemia (269 drugs)

Browse all the conditions that are associated with Hyperprolactinaemia:

Hyperprolactinaemia (387 conditions)

Drugs similar to Adderall and Hyperprolactinaemia :

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Adderall) and Adderall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.