Adderall and Sciatic nerve dysfunction - a phase IV clinical study of FDA data

Summary:

Sciatic nerve dysfunction is reported as a side effect among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Xyrem, and have Cataplexy.

The phase IV clinical study analyzes which people have Sciatic nerve dysfunction when taking Adderall. It is created by eHealthMe based on reports of 50,493 people who have side effects when taking Adderall from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,213 Adderall users. Check the latest studies of Adderall.

What is Sciatic nerve dysfunction?

Sciatic nerve dysfunction (a condition in which the sciatic nerve conducts impulses abnormally) is found to be associated with 1,918 drugs and 1,452 conditions by eHealthMe. Check the latest studies of Sciatic nerve dysfunction.

On Nov, 10, 2025

50,493 people reported to have side effects when taking Adderall.
Among them, 101 people (0.2%) have Sciatic nerve dysfunction.

Could Adderall cause Sciatic nerve dysfunction?

Among these 101 people:

How long have people been on Adderall when they have Sciatic nerve dysfunction? *

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What is the gender of people who have Sciatic nerve dysfunction when taking Adderall? *

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What is the age of people who have Sciatic nerve dysfunction when taking Adderall? *

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* Approximation only. Some reports may have incomplete information.

Do you take Adderall and have Sciatic nerve dysfunction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adderall:

Adderall (64,213 reports)

Sciatic nerve dysfunction treatments and more:

Sciatic nerve dysfunction (28,507 reports)

How severe was Sciatic nerve dysfunction and when was it recovered:

Sciatic nerve dysfunction in Adderall

Expand to all the drugs that have ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate:

Sciatic nerve dysfunction and drugs with ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (119 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Adderall side effects:

Adderall side effect: Fatigue (feeling of tiredness) (4,411 reports)

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sciatic nerve dysfunction:

Browse all the drugs that are associated with Sciatic nerve dysfunction:

Sciatic nerve dysfunction (1,918 drugs)

Common conditions associated with Sciatic nerve dysfunction:

Ra: 3,984 reports
Osteoporosis: 1,578 reports
Psoriatic arthropathy aggravated: 1,283 reports
Pain: 1,076 reports
Pain relief: 1,069 reports
Multiple sclerosis: 1,038 reports
Hypertension: 930 reports
Blood pressure increased: 922 reports
Blood cholesterol increased: 804 reports
Psoriasis: 785 reports

Browse all the conditions that are associated with Sciatic nerve dysfunction:

Sciatic nerve dysfunction (1,452 conditions)

Drugs similar to Adderall and Sciatic nerve dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Adderall) and Adderall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.