Adderall and Sedation - a phase IV clinical study of FDA data

Summary:

Sedation is reported as a side effect among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Xyrem, and have Cataplexy.

The phase IV clinical study analyzes which people have Sedation when taking Adderall. It is created by eHealthMe based on reports of 50,493 people who have side effects when taking Adderall from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,213 Adderall users. Check the latest studies of Adderall.

What is Sedation?

Sedation is found to be associated with 1,396 drugs and 1,274 conditions by eHealthMe. Check the latest studies of Sedation.

On Jan, 16, 2026

50,493 people reported to have side effects when taking Adderall.
Among them, 278 people (0.55%) have Sedation.

Among these 278 people:

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and have Sedation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adderall:

Adderall (64,213 reports)

Sedation treatments and more:

Sedation (52,223 reports)

How severe was Sedation and when was it recovered:

Sedation in Adderall

Expand to all the drugs that have ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate:

Sedation and drugs with ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (310 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Adderall side effects:

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sedation:

Browse all the drugs that are associated with Sedation:

Sedation (1,396 drugs)

Common conditions associated with Sedation:

Schizophrenia: 3,083 reports
Pain: 2,593 reports
Alternative medicine - pain relief: 2,574 reports
Depression: 2,431 reports
Hypertension: 1,538 reports
Htn: 1,535 reports
Acupuncture and pain: 1,197 reports
Difficulty falling asleep: 1,194 reports
Bipolar disorder: 1,096 reports
Bi-polar: 1,095 reports

Browse all the conditions that are associated with Sedation:

Sedation (1,274 conditions)

Drugs similar to Adderall and Sedation :

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Adderall) and Adderall (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.