Advil and Adrenal insufficiency - a phase IV clinical study of FDA data

Summary:

Adrenal insufficiency is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 50-59 old, also take Tylenol, and have Urinary tract infection.

The phase IV clinical study analyzes which people have Adrenal insufficiency when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Adrenal insufficiency?

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids) is found to be associated with 966 drugs and 1,093 conditions by eHealthMe. Check the latest studies of Adrenal insufficiency.

On Jul, 21, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 20 people (0.03%) have Adrenal insufficiency.

Could Advil cause Adrenal insufficiency?

Among these 20 people:

What is the gender of people who have Adrenal insufficiency when taking Advil? *

female: 70 %
male: 30 %

What is the age of people who have Adrenal insufficiency when taking Advil? *

What are other drugs people take besides Advil? *

What are other side effects people have besides Adrenal insufficiency? *

Fatigue (feeling of tiredness): 10 people, 50.00%
Sinusitis (inflammation of sinus): 8 people, 40.00%
Cough: 8 people, 40.00%
Fever: 8 people, 40.00%
Abdominal Pain: 7 people, 35.00%
Diarrhea: 7 people, 35.00%
Stress And Anxiety: 7 people, 35.00%
Atelectasis (partial or complete collapse of the lung): 7 people, 35.00%
Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 30.00%
Joint Pain: 6 people, 30.00%

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 3 people, 15.00%
Urinary Tract Infection: 3 people, 15.00%
Dehydration (dryness resulting from the removal of water): 2 people, 10.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 10.00%
Tumor: 2 people, 10.00%
Bone Pain: 2 people, 10.00%
Medullary Thyroid Cancer (type of thyroid cancer that develops in the parafollicular cells of the thyroid gland): 2 people, 10.00%
Hypokalemia (low potassium): 2 people, 10.00%
Weight Loss: 1 person, 5.00%
Back Pain: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Adrenal insufficiency?

- Check whether Adrenal insufficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Advil (62,533 reports)

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adrenal insufficiency:

Adrenal insufficiency (966 drugs)

Browse all the conditions that are associated with Adrenal insufficiency:

Adrenal insufficiency (1,093 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.