Advil and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Faslodex, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,447 drugs and 2,016 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.



On Apr, 14, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 42 people (0.07%) have Hepatic function abnormal.

Could Advil cause Hepatic function abnormal?

Among these 42 people:

How long have people been on Advil when they have Hepatic function abnormal? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hepatic function abnormal when taking Advil? *

  • female: 76.32 %
  • male: 23.68 %

What is the age of people who have Hepatic function abnormal when taking Advil? *

  • 0-1: 0.0 %
  • 2-9: 2.78 %
  • 10-19: 11.11 %
  • 20-29: 8.33 %
  • 30-39: 2.78 %
  • 40-49: 44.44 %
  • 50-59: 13.89 %
  • 60+: 16.67 %

What are other drugs people take besides Advil? *

  1. Zometa: 8 people, 19.05%
  2. Faslodex: 8 people, 19.05%
  3. Afinitor: 7 people, 16.67%
  4. Tylenol: 7 people, 16.67%
  5. Vicodin: 5 people, 11.90%
  6. Heparin: 4 people, 9.52%
  7. Keflex: 4 people, 9.52%
  8. Pantoprazole: 4 people, 9.52%
  9. Ranitidine: 4 people, 9.52%
  10. Cymbalta: 4 people, 9.52%

What are other side effects people have besides Hepatic function abnormal? *

  1. Thrombocytopenia (decrease of platelets in blood): 13 people, 30.95%
  2. Hypotension (abnormally low blood pressure): 13 people, 30.95%
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 11 people, 26.19%
  4. Fatigue (feeling of tiredness): 11 people, 26.19%
  5. Dizziness: 10 people, 23.81%
  6. Nausea (feeling of having an urge to vomit): 10 people, 23.81%
  7. Stress And Anxiety: 10 people, 23.81%
  8. Chills (felling of cold): 10 people, 23.81%
  9. Migraine (headache): 9 people, 21.43%
  10. Drug Ineffective: 9 people, 21.43%

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 7 people, 16.67%
  2. High Blood Pressure: 5 people, 11.90%
  3. Neuropathy Peripheral (surface nerve damage): 3 people, 7.14%
  4. Migraine (headache): 3 people, 7.14%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 7.14%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 7.14%
  7. Pain In Extremity: 2 people, 4.76%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.76%
  9. Back Pain: 2 people, 4.76%
  10. Nausea (feeling of having an urge to vomit): 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Hepatic function abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Hepatic function abnormal treatments and more:

How severe was Hepatic function abnormal and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic function abnormal:

Browse all the conditions that are associated with Hepatic function abnormal:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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