Advil and Oesophagitis aggravated - a phase IV clinical study of FDA data

Summary:

Oesophagitis aggravated is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Accutane, and have Acne.

The phase IV clinical study analyzes which people have Oesophagitis aggravated when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

What is Oesophagitis aggravated?

Oesophagitis aggravated (inflammation of oesophagus) is found to be associated with 971 drugs and 380 conditions by eHealthMe. Check the latest studies of Oesophagitis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 95 people (0.16%) have Oesophagitis aggravated.

Could Advil cause Oesophagitis aggravated?

Among these 95 people:

How long have people been on Advil when they have Oesophagitis aggravated? *

  • < 1 month: 28.57 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 14.29 %
  • 2 - 5 years: 42.86 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 14.29 %

What is the gender of people who have Oesophagitis aggravated when taking Advil? *

  • female: 55.17 %
  • male: 44.83 %

What is the age of people who have Oesophagitis aggravated when taking Advil? *

  • 0-1: 0.0 %
  • 2-9: 3.85 %
  • 10-19: 17.95 %
  • 20-29: 10.26 %
  • 30-39: 3.85 %
  • 40-49: 14.1 %
  • 50-59: 7.69 %
  • 60+: 42.31 %

What are other drugs people take besides Advil? *

  1. Accutane: 18 people, 18.95%
  2. Amnesteem: 14 people, 14.74%
  3. Sotret: 14 people, 14.74%
  4. Vioxx: 12 people, 12.63%
  5. Celebrex: 12 people, 12.63%
  6. Enbrel: 12 people, 12.63%
  7. Nexium: 12 people, 12.63%
  8. Zyrtec: 12 people, 12.63%
  9. Neurontin: 11 people, 11.58%
  10. Zometa: 11 people, 11.58%

What are other side effects people have besides Oesophagitis aggravated? *

  1. Gastritis (inflammation of stomach): 32 people, 33.68%
  2. Anaemia (lack of blood): 30 people, 31.58%
  3. Dyspnea (difficult or laboured breathing): 22 people, 23.16%
  4. Depression: 18 people, 18.95%
  5. Dehydration (dryness resulting from the removal of water): 18 people, 18.95%
  6. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 18 people, 18.95%
  7. Fall: 18 people, 18.95%
  8. Inflammatory Bowel Disease: 18 people, 18.95%
  9. Weight Decreased: 17 people, 17.89%
  10. Chest Pain: 17 people, 17.89%

What are the existing conditions these people have? *

  1. Acne (skin problems that cause pimples): 14 people, 14.74%
  2. High Blood Pressure: 8 people, 8.42%
  3. Back Pain: 3 people, 3.16%
  4. Inflammation: 3 people, 3.16%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 3.16%
  6. Muscle Aches (muscle pain): 3 people, 3.16%
  7. Oedema (fluid collection in tissue): 2 people, 2.11%
  8. Asthma: 2 people, 2.11%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 2.11%
  10. Itching: 2 people, 2.11%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Oesophagitis aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Oesophagitis aggravated treatments and more:

How severe was Oesophagitis aggravated and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oesophagitis aggravated:

Browse all the conditions that are associated with Oesophagitis aggravated:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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