Advil and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Rickets when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,088 drugs and 1,459 conditions by eHealthMe. Check the latest studies of Rickets.

On Jul, 26, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 71 people (0.12%) have Rickets.

Among these 71 people:

How long have people been on Advil when they have Rickets? *

What is the gender of people who have Rickets when taking Advil? *

female: 80.88 %
male: 19.12 %

What is the age of people who have Rickets when taking Advil? *

What are other drugs people take besides Advil? *

What are other side effects people have besides Rickets? *

Nausea (feeling of having an urge to vomit): 19 people, 26.76%
Weakness: 19 people, 26.76%
Joint Pain: 19 people, 26.76%
Depression: 17 people, 23.94%
Osteoporosis (bones weak and more likely to break): 16 people, 22.54%
Stress And Anxiety: 16 people, 22.54%
Dizziness: 15 people, 21.13%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 15 people, 21.13%
Urinary Tract Infection: 15 people, 21.13%
Fatigue (feeling of tiredness): 14 people, 19.72%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 19.72%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 16.90%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 9.86%
Osteoporosis (bones weak and more likely to break): 7 people, 9.86%
Indigestion: 6 people, 8.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 7.04%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 7.04%
Sleep Disorder: 5 people, 7.04%
High Blood Pressure: 5 people, 7.04%
Joint Pain: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Rickets?

- Check whether Rickets is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Advil (62,533 reports)

Rickets treatments and more:

Rickets (30,776 reports)

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Rickets (1,088 drugs)

Browse all the conditions that are associated with Rickets:

Rickets (1,459 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.