Afinitor and Muscle atrophy - a phase IV clinical study of FDA data

Summary:

Muscle atrophy is reported as a side effect among people who take Afinitor (everolimus), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Dipyrone, and have Neuroendocrine tumor.

The phase IV clinical study analyzes which people have Muscle atrophy when taking Afinitor. It is created by eHealthMe based on reports of 41,609 people who have side effects when taking Afinitor from the FDA, and is updated regularly.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

What is Muscle atrophy?

Muscle atrophy (a decrease in the mass of the muscle) is found to be associated with 1,045 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Muscle atrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

41,609 people reported to have side effects when taking Afinitor.
Among them, 17 people (0.04%) have Muscle atrophy.

Among these 17 people:

How long have people been on Afinitor when they have Muscle atrophy? *

What is the gender of people who have Muscle atrophy when taking Afinitor? *

female: 47.06 %
male: 52.94 %

What is the age of people who have Muscle atrophy when taking Afinitor? *

What are other drugs people take besides Afinitor? *

What are other side effects people have besides Muscle atrophy? *

Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 47.06%
Weight Decreased: 8 people, 47.06%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 41.18%
Fatigue (feeling of tiredness): 7 people, 41.18%
Weakness: 6 people, 35.29%
Injection Site Pain: 6 people, 35.29%
Gait Disturbance: 6 people, 35.29%
Nausea (feeling of having an urge to vomit): 6 people, 35.29%
Nausea And Vomiting: 5 people, 29.41%
Pain: 4 people, 23.53%

What are the existing conditions these people have? *

Neuroendocrine Tumor: 6 people, 35.29%
Pain: 3 people, 17.65%
Gastric Disorder (disease of stomach): 3 people, 17.65%
Cardiac Disorder: 3 people, 17.65%
Renal Cell Carcinoma (a kidney cancer): 2 people, 11.76%
Pancreatic Neuroendocrine Tumor: 2 people, 11.76%
Carcinoid Tumor: 2 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Renal Neoplasm (kidney tumour): 1 person, 5.88%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Afinitor and have Muscle atrophy?

- Check whether Muscle atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Afinitor:

Afinitor (41,680 reports)

Muscle atrophy treatments and more:

Muscle atrophy (15,319 reports)

Browse all side effects of Afinitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle atrophy:

Muscle atrophy (1,045 drugs)

Browse all the conditions that are associated with Muscle atrophy:

Muscle atrophy (1,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on everolimus (the active ingredients of Afinitor) and Afinitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.