Afinitor and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Afinitor (everolimus), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sutent, and have Pancreatic neuroendocrine tumor.

The phase IV clinical study analyzes which people have Sciatica when taking Afinitor. It is created by eHealthMe based on reports of 41,609 people who have side effects when taking Afinitor from the FDA, and is updated regularly.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,144 drugs and 1,428 conditions by eHealthMe. Check the latest studies of Sciatica.

On Apr, 13, 2026

41,609 people reported to have side effects when taking Afinitor.
Among them, 41 people (0.1%) have Sciatica.

Among these 41 people:

How long have people been on Afinitor when they have Sciatica? *

What is the gender of people who have Sciatica when taking Afinitor? *

female: 42.11 %
male: 57.89 %

What is the age of people who have Sciatica when taking Afinitor? *

What are other drugs people take besides Afinitor? *

What are other side effects people have besides Sciatica? *

Pain: 24 people, 58.54%
Abdominal Pain: 22 people, 53.66%
Malaise (a feeling of general discomfort or uneasiness): 19 people, 46.34%
Pain In Extremity: 18 people, 43.90%
Diarrhea: 18 people, 43.90%
Weight Decreased: 17 people, 41.46%
Back Pain: 17 people, 41.46%
Fatigue (feeling of tiredness): 14 people, 34.15%
Malignant Neoplasm Progression (cancer tumour came back): 14 people, 34.15%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 13 people, 31.71%

What are the existing conditions these people have? *

Pancreatic Neuroendocrine Tumor: 11 people, 26.83%
Renal Cell Carcinoma (a kidney cancer): 8 people, 19.51%
Pancreatic Neuroendocrine Tumor Metastatic: 8 people, 19.51%
Neuroendocrine Tumor: 8 people, 19.51%
High Blood Pressure: 6 people, 14.63%
Device Related Infection: 5 people, 12.20%
Metastases To Spine (cancer spreads to spine): 5 people, 12.20%
Type 2 Diabetes: 4 people, 9.76%
Carcinoid Tumor: 2 people, 4.88%
Weakness: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Afinitor and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Afinitor:

Afinitor (41,680 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Afinitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,144 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,428 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on everolimus (the active ingredients of Afinitor) and Afinitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.