Afrezza and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Afrezza (insulin recombinant human), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Humalog, and have Diabetes.

The phase IV clinical study analyzes which people have Malaise when taking Afrezza. It is created by eHealthMe based on reports of 1,137 people who have side effects when taking Afrezza from the FDA, and is updated regularly.

What is Afrezza?

Afrezza has active ingredients of insulin recombinant human. eHealthMe is studying from 1,138 Afrezza users. Check the latest studies of Afrezza.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,513 drugs and 5,120 conditions by eHealthMe. Check the latest studies of Malaise.

On Jul, 16, 2026

1,137 people reported to have side effects when taking Afrezza.
Among them, 12 people (1.06%) have Malaise.

Among these 12 people:

How long have people been on Afrezza when they have Malaise? *

What is the gender of people who have Malaise when taking Afrezza? *

female: 75 %
male: 25 %

What is the age of people who have Malaise when taking Afrezza? *

What are other drugs people take besides Afrezza? *

What are other side effects people have besides Malaise? *

Nausea (feeling of having an urge to vomit): 4 people, 33.33%
Chest Pain: 3 people, 25.00%
Cough: 2 people, 16.67%
Weakness: 2 people, 16.67%
Lung Disorder (lung disease): 2 people, 16.67%
Blood Glucose Abnormal: 2 people, 16.67%
Stress And Anxiety: 2 people, 16.67%
Pain In Extremity: 2 people, 16.67%
Blood Glucose Increased: 2 people, 16.67%
Dyspnea (difficult or laboured breathing): 2 people, 16.67%

What are the existing conditions these people have? *

Diabetes: 4 people, 33.33%
Type 1 Diabetes: 2 people, 16.67%
Type 2 Diabetes: 1 person, 8.33%
Insomnia (sleeplessness): 1 person, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Cushing's Syndrome (obesity, a rounded face, increased fat): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Afrezza and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Afrezza:

Afrezza (1,138 reports)

Malaise treatments and more:

Malaise (529,933 reports)

Browse all side effects of Afrezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Malaise (3,513 drugs)

Browse all the conditions that are associated with Malaise:

Malaise (5,120 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on insulin recombinant human (the active ingredients of Afrezza) and Afrezza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.