Akineton and Pruritus aggravated - a phase IV clinical study of FDA data

Summary:

Pruritus aggravated is reported as a side effect among people who take Akineton (biperiden hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Zyprexa, and have Schizophrenia.

The phase IV clinical study analyzes which people have Pruritus aggravated when taking Akineton. It is created by eHealthMe based on reports of 6,101 people who have side effects when taking Akineton from the FDA, and is updated regularly.

What is Akineton?

Akineton has active ingredients of biperiden hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 6,140 Akineton users. Check the latest studies of Akineton.

What is Pruritus aggravated?

Pruritus aggravated (serious severe itching of the skin) is found to be associated with 2,481 drugs and 1,069 conditions by eHealthMe. Check the latest studies of Pruritus aggravated.

On Jul, 21, 2026

6,101 people reported to have side effects when taking Akineton.
Among them, 64 people (1.05%) have Pruritus aggravated.

Could Akineton cause Pruritus aggravated?

Among these 64 people:

How long have people been on Akineton when they have Pruritus aggravated? *

What is the gender of people who have Pruritus aggravated when taking Akineton? *

female: 59.68 %
male: 40.32 %

What is the age of people who have Pruritus aggravated when taking Akineton? *

What are other drugs people take besides Akineton? *

What are other side effects people have besides Pruritus aggravated? *

Rashes (redness): 23 people, 35.94%
Fever: 12 people, 18.75%
Alanine Aminotransferase Increased: 9 people, 14.06%
Constipation: 9 people, 14.06%
Weight Increased: 7 people, 10.94%
Aspartate Aminotransferase Increased: 7 people, 10.94%
Abdominal Pain: 7 people, 10.94%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 10.94%
Swelling Face: 6 people, 9.38%
Akathisia (a movement disorder characterized by a feeling of inner restlessness): 6 people, 9.38%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 13 people, 20.31%
Depression: 7 people, 10.94%
Bipolar Disorder (mood disorder): 6 people, 9.38%
Dyslipidaemia (abnormal amount of lipids): 4 people, 6.25%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 6.25%
Hypertriglyceridaemia (excess of triglycerides in the blood): 4 people, 6.25%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 4.69%
Coordination Abnormal (abnormal movement): 2 people, 3.12%
Stress And Anxiety: 2 people, 3.12%
High Blood Pressure: 2 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Akineton and have Pruritus aggravated?

- Check whether Pruritus aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Akineton:

Akineton (6,140 reports)

Browse all side effects of Akineton:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pruritus aggravated:

Pruritus aggravated (2,481 drugs)

Browse all the conditions that are associated with Pruritus aggravated:

Pruritus aggravated (1,069 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on biperiden hydrochloride (the active ingredients of Akineton) and Akineton (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.