Aldactone and Eye irritation - a phase IV clinical study of FDA data

Summary:

Eye irritation is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, also take Lasix, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Eye irritation when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Eye irritation?

Eye irritation is found to be associated with 1,296 drugs and 1,287 conditions by eHealthMe. Check the latest studies of Eye irritation.

On Jul, 17, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 36 people (0.08%) have Eye irritation.

Among these 36 people:

What is the gender of people who have Eye irritation when taking Aldactone? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Eye irritation when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Eye irritation? *

Pain: 11 people, 30.56%
Nausea (feeling of having an urge to vomit): 10 people, 27.78%
Dry Eyes (lack of adequate tears): 10 people, 27.78%
Weakness: 9 people, 25.00%
Fatigue (feeling of tiredness): 9 people, 25.00%
Fainting (loss of consciousness and postural tone): 9 people, 25.00%
Nausea And Vomiting: 8 people, 22.22%
Pain In Extremity: 8 people, 22.22%
Dyspnea (difficult or laboured breathing): 8 people, 22.22%
Hyperhidrosis (abnormally increased sweating): 8 people, 22.22%

What are the existing conditions these people have? *

High Blood Cholesterol: 6 people, 16.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 13.89%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 11.11%
Depression: 3 people, 8.33%
Neuralgia (pain in one or more nerves): 3 people, 8.33%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 8.33%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 3 people, 8.33%
Cardiac Disorder: 3 people, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.56%
Cardiac Murmur (an heart sound in valve abnormality): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Eye irritation?

- Check whether Eye irritation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Eye irritation treatments and more:

Eye irritation (50,674 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eye irritation:

Eye irritation (1,296 drugs)

Browse all the conditions that are associated with Eye irritation:

Eye irritation (1,287 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.