Aldactone and Peptic ulcer aggravated - a phase IV clinical study of FDA data

Summary:

Peptic ulcer aggravated is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lasix, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Peptic ulcer aggravated when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Peptic ulcer aggravated?

Peptic ulcer aggravated is found to be associated with 1,495 drugs and 548 conditions by eHealthMe. Check the latest studies of Peptic ulcer aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 384 people (0.85%) have Peptic ulcer aggravated.

Could Aldactone cause Peptic ulcer aggravated?

Among these 384 people:

How long have people been on Aldactone when they have Peptic ulcer aggravated? *

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What is the gender of people who have Peptic ulcer aggravated when taking Aldactone? *

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What is the age of people who have Peptic ulcer aggravated when taking Aldactone? *

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* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Peptic ulcer aggravated?

- Check whether Peptic ulcer aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Peptic ulcer aggravated treatments and more:

Peptic ulcer aggravated (42 reports)

How severe was Peptic ulcer aggravated and when was it recovered:

Peptic ulcer aggravated in Aldactone

Expand to all the drugs that have ingredients of spironolactone:

Peptic ulcer aggravated and drugs with ingredients of spironolactone

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (1,495 drugs)

Browse all the conditions that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (548 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.