Alesse and Gallbladder disorder - a phase IV clinical study of FDA data

Summary:

Gallbladder disorder is reported as a side effect among people who take Alesse (ethinyl estradiol; levonorgestrel), especially for people who are female, 30-39 old, have been taking the drug for 6 - 12 months also take Yasmin, and have Acne.

The phase IV clinical study analyzes which people have Gallbladder disorder when taking Alesse. It is created by eHealthMe based on reports of 3,150 people who have side effects when taking Alesse from the FDA, and is updated regularly.

What is Alesse?

Alesse has active ingredients of ethinyl estradiol; levonorgestrel. It is often used in birth control. eHealthMe is studying from 3,353 Alesse users. Check the latest studies of Alesse.

What is Gallbladder disorder?

Gallbladder disorder is found to be associated with 1,191 drugs and 1,786 conditions by eHealthMe. Check the latest studies of Gallbladder disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

3,150 people reported to have side effects when taking Alesse.
Among them, 15 people (0.48%) have Gallbladder disorder.

Could Alesse cause Gallbladder disorder?

Among these 15 people:

How long have people been on Alesse when they have Gallbladder disorder? *

What is the gender of people who have Gallbladder disorder when taking Alesse? *

female: 100 %
male: 0.0 %

What is the age of people who have Gallbladder disorder when taking Alesse? *

What are other drugs people take besides Alesse? *

Yaz: 8 people, 53.33%
Yasmin: 8 people, 53.33%
Depo-Medrol: 3 people, 20.00%
Gabapentin: 3 people, 20.00%
Synthroid: 3 people, 20.00%
Albuterol: 3 people, 20.00%
Drospirenone And Ethinyl Estradiol: 3 people, 20.00%
Psyllium: 3 people, 20.00%
Lamictal: 2 people, 13.33%
Motrin: 2 people, 13.33%

What are other side effects people have besides Gallbladder disorder? *

Cholecystitis Chronic (long lasting infection of gallbladder): 12 people, 80.00%
Pain: 6 people, 40.00%
Abdominal Pain: 5 people, 33.33%
Stress And Anxiety: 5 people, 33.33%
Injury: 3 people, 20.00%
Nausea And Vomiting: 3 people, 20.00%
Nausea (feeling of having an urge to vomit): 3 people, 20.00%
Abdominal Pain Upper: 3 people, 20.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 2 people, 13.33%
Food Intolerance (inability to have food): 2 people, 13.33%

What are the existing conditions these people have? *

Acne (skin problems that cause pimples): 3 people, 20.00%
Premenstrual Syndrome: 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Depression: 2 people, 13.33%
Asthma: 2 people, 13.33%
Urinary Tract Infection: 1 person, 6.67%
Thyroid Cancer: 1 person, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%
Dysmenorrhea (painful menstruation): 1 person, 6.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Alesse and have Gallbladder disorder?

- Check whether Gallbladder disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alesse:

Alesse (3,353 reports)

Gallbladder disorder treatments and more:

Gallbladder disorder (27,083 reports)

How severe was Gallbladder disorder and when was it recovered:

Gallbladder disorder in Alesse

Expand to all the drugs that have ingredients of ethinyl estradiol; levonorgestrel:

Gallbladder disorder and drugs with ingredients of ethinyl estradiol; levonorgestrel (157 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alesse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder disorder:

Gallbladder disorder (1,191 drugs)

Browse all the conditions that are associated with Gallbladder disorder:

Gallbladder disorder (1,786 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; levonorgestrel (the active ingredients of Alesse) and Alesse (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.