Alesse and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Alesse (ethinyl estradiol; levonorgestrel), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Effexor, and have Crohn's disease.

The phase IV clinical study analyzes which people have Weakness when taking Alesse. It is created by eHealthMe based on reports of 3,150 people who have side effects when taking Alesse from the FDA, and is updated regularly.

What is Alesse?

Alesse has active ingredients of ethinyl estradiol; levonorgestrel. It is often used in birth control. eHealthMe is studying from 3,353 Alesse users. Check the latest studies of Alesse.

What is Weakness?

Weakness is found to be associated with 3,639 drugs and 6,612 conditions by eHealthMe. Check the latest studies of Weakness.

On Jul, 18, 2026

3,150 people reported to have side effects when taking Alesse.
Among them, 64 people (2.03%) have Weakness.

Among these 64 people:

How long have people been on Alesse when they have Weakness? *

What is the gender of people who have Weakness when taking Alesse? *

female: 100 %
male: 0.0 %

What is the age of people who have Weakness when taking Alesse? *

What are other drugs people take besides Alesse? *

What are other side effects people have besides Weakness? *

Nausea (feeling of having an urge to vomit): 16 people, 25.00%
Headache (pain in head): 12 people, 18.75%
Muscle Aches (muscle pain): 11 people, 17.19%
Depression: 10 people, 15.62%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 9 people, 14.06%
Acute Kidney Failure: 9 people, 14.06%
Uveitis (inflammation of the uvea): 9 people, 14.06%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 14.06%
Pain In Extremity: 9 people, 14.06%
Inflammatory Bowel Disease: 9 people, 14.06%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 15.62%
Upper Respiratory Tract Infection: 9 people, 14.06%
Kidney Infection (Pyelonephritis): 9 people, 14.06%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 9 people, 14.06%
Depression: 9 people, 14.06%
Acne (skin problems that cause pimples): 9 people, 14.06%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 5 people, 7.81%
Menstruation Irregular: 1 person, 1.56%
Pain: 1 person, 1.56%
Joint Pain: 1 person, 1.56%

* Approximation only. Some reports may have incomplete information.

Do you take Alesse and have Weakness?

- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alesse:

Alesse (3,353 reports)

Weakness treatments and more:

Weakness (586,876 reports)

How severe was Weakness and when was it recovered:

Weakness in Alesse

Expand to all the drugs that have ingredients of ethinyl estradiol; levonorgestrel:

Weakness and drugs with ingredients of ethinyl estradiol; levonorgestrel (492 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alesse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Weakness (3,639 drugs)

Browse all the conditions that are associated with Weakness:

Weakness (6,612 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; levonorgestrel (the active ingredients of Alesse) and Alesse (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.