Aleve and Polyuria - a phase IV clinical study of FDA data

Summary:

Polyuria is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Sleep disorder.

The phase IV clinical study analyzes which people have Polyuria when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,277 Aleve users. Check the latest studies of Aleve.

What is Polyuria?

Polyuria (production of too much dilute urine) is found to be associated with 1,704 drugs and 1,272 conditions by eHealthMe. Check the latest studies of Polyuria.

On Oct, 22, 2025

68,206 people reported to have side effects when taking Aleve.
Among them, 25 people (0.04%) have Polyuria.

Among these 25 people:

How long have people been on Aleve when they have Polyuria? *

What is the gender of people who have Polyuria when taking Aleve? *

female: 68 %
male: 32 %

What is the age of people who have Polyuria when taking Aleve? *

What are other drugs people take besides Aleve? *

What are other side effects people have besides Polyuria? *

High Blood Pressure: 9 people, 36.00%
Stress And Anxiety: 8 people, 32.00%
Dizziness: 7 people, 28.00%
Indigestion: 7 people, 28.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 28.00%
Stable Angina (a constant chest pain): 7 people, 28.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 7 people, 28.00%
Fatigue (feeling of tiredness): 7 people, 28.00%
Nausea (feeling of having an urge to vomit): 7 people, 28.00%
Carotid Artery Stenosis (narrowing of carotid artery): 7 people, 28.00%

What are the existing conditions these people have? *

Sleep Disorder: 5 people, 20.00%
Joint Stiffness: 3 people, 12.00%
Weakness: 1 person, 4.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 4.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 4.00%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 1 person, 4.00%
Neck Pain: 1 person, 4.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.00%
High Blood Pressure: 1 person, 4.00%
Flatulence (flatus expelled through the anus): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Polyuria?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Aleve (70,277 reports)

Polyuria treatments and more:

Polyuria (15,800 reports)

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Polyuria:

Polyuria (1,704 drugs)

Browse all the conditions that are associated with Polyuria:

Polyuria (1,272 conditions)

Drugs similar to Aleve and Polyuria :

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.