Oxycontin and Polyuria - a phase IV clinical study of FDA data

Summary:

Polyuria is reported as a side effect among people who take Oxycontin (oxycodone hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for 10+ years also take Neurontin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Polyuria when taking Oxycontin. It is created by eHealthMe based on reports of 210,595 people who have side effects when taking Oxycontin from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,532 Oxycontin users. Check the latest studies of Oxycontin.

What is Polyuria?

Polyuria (production of too much dilute urine) is found to be associated with 1,724 drugs and 1,271 conditions by eHealthMe. Check the latest studies of Polyuria.



On Sep, 08, 2025

210,595 people reported to have side effects when taking Oxycontin.
Among them, 87 people (0.04%) have Polyuria.

Could Oxycontin cause Polyuria?

Among these 87 people:

How long have people been on Oxycontin when they have Polyuria? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 20.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 46.67 %

What is the gender of people who have Polyuria when taking Oxycontin? *

  • female: 21.69 %
  • male: 78.31 %

What is the age of people who have Polyuria when taking Oxycontin? *

  • 0-1: 0.0 %
  • 2-9: 1.43 %
  • 10-19: 0.0 %
  • 20-29: 4.29 %
  • 30-39: 8.57 %
  • 40-49: 44.29 %
  • 50-59: 28.57 %
  • 60+: 12.86 %

What are other drugs people take besides Oxycontin? *

  1. Neurontin: 39 people, 44.83%
  2. Percocet: 29 people, 33.33%
  3. Flexeril: 28 people, 32.18%
  4. Vioxx: 24 people, 27.59%
  5. Zanaflex: 24 people, 27.59%
  6. Prilosec: 23 people, 26.44%
  7. Valium: 21 people, 24.14%
  8. Zometa: 21 people, 24.14%
  9. Baclofen: 21 people, 24.14%
  10. Ambien: 20 people, 22.99%

What are other side effects people have besides Polyuria? *

  1. Hypoaesthesia (reduced sense of touch or sensation): 49 people, 56.32%
  2. Stress And Anxiety: 43 people, 49.43%
  3. Drug Dependence: 43 people, 49.43%
  4. Nausea (feeling of having an urge to vomit): 42 people, 48.28%
  5. Nausea And Vomiting: 40 people, 45.98%
  6. Depression: 37 people, 42.53%
  7. Weakness: 36 people, 41.38%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 35 people, 40.23%
  9. Constipation: 35 people, 40.23%
  10. Joint Pain: 31 people, 35.63%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 21 people, 24.14%
  2. Sleep Disorder: 8 people, 9.20%
  3. Insomnia (sleeplessness): 8 people, 9.20%
  4. Facial Pain: 3 people, 3.45%
  5. High Blood Pressure: 3 people, 3.45%
  6. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 3.45%
  7. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 3 people, 3.45%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 3.45%
  9. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 3.45%
  10. Osteoporosis (bones weak and more likely to break): 2 people, 2.30%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and have Polyuria?

- Check whether Polyuria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycontin:

Polyuria treatments and more:

How severe was Polyuria and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Polyuria:

Browse all the conditions that are associated with Polyuria:

Drugs similar to Oxycontin and Polyuria :


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycontin) and Oxycontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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