Alimta and Hypovolaemia - a phase IV clinical study of FDA data

Summary:

Hypovolaemia is reported as a side effect among people who take Alimta (pemetrexed disodium), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Folic Acid, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Hypovolaemia when taking Alimta. It is created by eHealthMe based on reports of 7,644 people who have side effects when taking Alimta from the FDA, and is updated regularly.

What is Alimta?

Alimta has active ingredients of pemetrexed disodium. eHealthMe is studying from 7,702 Alimta users. Check the latest studies of Alimta.

What is Hypovolaemia?

Hypovolaemia (a decreased volume of circulating blood in the body) is found to be associated with 893 drugs and 837 conditions by eHealthMe. Check the latest studies of Hypovolaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

7,644 people reported to have side effects when taking Alimta.
Among them, 12 people (0.16%) have Hypovolaemia.

Could Alimta cause Hypovolaemia?

Among these 12 people:

How long have people been on Alimta when they have Hypovolaemia? *

  • < 1 month: 42.86 %
  • 1 - 6 months: 57.14 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypovolaemia when taking Alimta? *

  • female: 36.36 %
  • male: 63.64 %

What is the age of people who have Hypovolaemia when taking Alimta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 83.33 %

What are other drugs people take besides Alimta? *

  1. Folic Acid: 4 people, 33.33%
  2. Zofran: 2 people, 16.67%
  3. Glycolax: 2 people, 16.67%
  4. Aleve: 2 people, 16.67%
  5. Aspirin: 2 people, 16.67%
  6. Buspar: 2 people, 16.67%
  7. Cardizem: 2 people, 16.67%
  8. Depakote: 2 people, 16.67%
  9. Gemcitabine: 2 people, 16.67%
  10. Gemfibrozil: 2 people, 16.67%

What are other side effects people have besides Hypovolaemia? *

  1. Hypotension (abnormally low blood pressure): 6 people, 50.00%
  2. Anaemia (lack of blood): 5 people, 41.67%
  3. Acute Kidney Failure: 5 people, 41.67%
  4. Thrombocytopenia (decrease of platelets in blood): 4 people, 33.33%
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 33.33%
  6. Chills (felling of cold): 3 people, 25.00%
  7. Disease Progression: 3 people, 25.00%
  8. Nausea (feeling of having an urge to vomit): 3 people, 25.00%
  9. Fever: 3 people, 25.00%
  10. Gallstones (stone formation by bile component): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 25.00%
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 16.67%
  3. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 2 people, 16.67%
  4. Pain: 2 people, 16.67%
  5. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 16.67%
  6. Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 16.67%
  7. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 8.33%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
  9. Constipation: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Alimta and have Hypovolaemia?

- Check whether Hypovolaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alimta:

Hypovolaemia treatments and more:

How severe was Hypovolaemia and when was it recovered:

Expand to all the drugs that have ingredients of pemetrexed disodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alimta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypovolaemia:

Browse all the conditions that are associated with Hypovolaemia:


How the study uses the data?

The study uses data from the FDA. It is based on pemetrexed disodium (the active ingredients of Alimta) and Alimta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: