Alkeran and Bleeding into the skin - a phase IV clinical study of FDA data

Summary:

Bleeding into the skin is reported as a side effect among people who take Alkeran (melphalan), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Bactrim, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Bleeding into the skin when taking Alkeran. It is created by eHealthMe based on reports of 5,418 people who have side effects when taking Alkeran from the FDA, and is updated regularly.

What is Alkeran?

Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.

What is Bleeding into the skin?

Bleeding into the skin is found to be associated with 937 drugs and 1,909 conditions by eHealthMe. Check the latest studies of Bleeding into the skin.

On Jul, 16, 2026

5,418 people reported to have side effects when taking Alkeran.
Among them, 27 people (0.5%) have Bleeding into the skin.

Could Alkeran cause Bleeding into the skin?

Among these 27 people:

How long have people been on Alkeran when they have Bleeding into the skin? *

What is the gender of people who have Bleeding into the skin when taking Alkeran? *

female: 79.17 %
male: 20.83 %

What is the age of people who have Bleeding into the skin when taking Alkeran? *

What are other drugs people take besides Alkeran? *

What are other side effects people have besides Bleeding into the skin? *

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 5 people, 18.52%
Fever: 5 people, 18.52%
Rashes (redness): 5 people, 18.52%
Palmar Erythema (reddening of the palms at the thenar and hypothenar eminences): 3 people, 11.11%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 11.11%
Diarrhea: 3 people, 11.11%
Culture Stool Positive: 3 people, 11.11%
Abdominal Pain: 3 people, 11.11%
Bone Marrow Failure: 3 people, 11.11%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 3 people, 11.11%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 29.63%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 3.70%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Alkeran and have Bleeding into the skin?

- Check whether Bleeding into the skin is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alkeran:

Alkeran (5,429 reports)

Browse all side effects of Alkeran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bleeding into the skin:

Bleeding into the skin (937 drugs)

Browse all the conditions that are associated with Bleeding into the skin:

Bleeding into the skin (1,909 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on melphalan (the active ingredients of Alkeran) and Alkeran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.