Alkeran and Hypercalcaemia aggravated - a phase IV clinical study of FDA data
Summary:
Hypercalcaemia aggravated is reported as a side effect among people who take Alkeran (melphalan), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Zometa, and have Multiple myeloma.
The phase IV clinical study analyzes which people have Hypercalcaemia aggravated when taking Alkeran. It is created by eHealthMe based on reports of 5,418 people who have side effects when taking Alkeran from the FDA, and is updated regularly.
What is Alkeran?
Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.
What is Hypercalcaemia aggravated?
Hypercalcaemia aggravated (elevated calcium (ca+) level in the blood. (norma) is found to be associated with 933 drugs and 343 conditions by eHealthMe. Check the latest studies of Hypercalcaemia aggravated.
5,418 people reported to have side effects when taking Alkeran.
Among them, 53 people (0.98%) have Hypercalcaemia aggravated.

Among these 53 people:
How long have people been on Alkeran when they have Hypercalcaemia aggravated? *
- < 1 month: 0.0 %
- 1 - 6 months: 20 %
- 6 - 12 months: 80 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hypercalcaemia aggravated when taking Alkeran? *
- female: 73.47 %
- male: 26.53 %
What is the age of people who have Hypercalcaemia aggravated when taking Alkeran? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 1.96 %
- 40-49: 3.92 %
- 50-59: 23.53 %
- 60+: 70.59 %
What are other drugs people take besides Alkeran? *
- Zometa: 42 people, 79.25%
- Aredia: 37 people, 69.81%
- Prednisone: 33 people, 62.26%
- Revlimid: 27 people, 50.94%
- Nexium: 26 people, 49.06%
- Levaquin: 25 people, 47.17%
- Neurontin: 24 people, 45.28%
- Prilosec: 23 people, 43.40%
- Cymbalta: 23 people, 43.40%
- Vioxx: 23 people, 43.40%
What are other side effects people have besides Hypercalcaemia aggravated? *
- Pain: 35 people, 66.04%
- Osteonecrosis Of Jaw (death of bone of jaw): 35 people, 66.04%
- Joint Pain: 32 people, 60.38%
- Weakness: 30 people, 56.60%
- Leukopenia (less number of white blood cells in blood): 29 people, 54.72%
- Fatigue (feeling of tiredness): 28 people, 52.83%
- Urinary Tract Infection: 28 people, 52.83%
- Deformity (disfigurement): 28 people, 52.83%
- Pain In Extremity: 27 people, 50.94%
- Fall: 27 people, 50.94%
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 43 people, 81.13%
- Diabetes: 5 people, 9.43%
- Osteolysis (dissolution of bone): 2 people, 3.77%
- Osteoporosis (bones weak and more likely to break): 1 person, 1.89%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 1.89%
- Metastases To Bone (cancer spreads to bone): 1 person, 1.89%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 1.89%
- High Blood Pressure: 1 person, 1.89%
- Depression: 1 person, 1.89%
- Bone Loss: 1 person, 1.89%
* Approximation only. Some reports may have incomplete information.
Do you take Alkeran and have Hypercalcaemia aggravated?
- Check whether Hypercalcaemia aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Alkeran:
- Alkeran (5,429 reports)
Hypercalcaemia aggravated treatments and more:
- Hypercalcaemia aggravated (1 reports)
How severe was Hypercalcaemia aggravated and when was it recovered:
Expand to all the drugs that have ingredients of melphalan:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alkeran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypercalcaemia aggravated:
- Hypercalcaemia aggravated (933 drugs)
Browse all the conditions that are associated with Hypercalcaemia aggravated:
- Hypercalcaemia aggravated (343 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on melphalan (the active ingredients of Alkeran) and Alkeran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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