Alkeran and Skin ulcer - a phase IV clinical study of FDA data
Summary:
Skin ulcer is reported as a side effect among people who take Alkeran (melphalan), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Velcade, and have Acute myeloid leukaemia.
The phase IV clinical study analyzes which people have Skin ulcer when taking Alkeran. It is created by eHealthMe based on reports of 5,418 people who have side effects when taking Alkeran from the FDA, and is updated regularly.
What is Alkeran?
Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.
What is Skin ulcer?
Skin ulcer is found to be associated with 1,452 drugs and 1,482 conditions by eHealthMe. Check the latest studies of Skin ulcer.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
5,418 people reported to have side effects when taking Alkeran.
Among them, 11 people (0.2%) have Skin ulcer.

Among these 11 people:
How long have people been on Alkeran when they have Skin ulcer? *
- < 1 month: 66.67 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 33.33 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Skin ulcer when taking Alkeran? *
- female: 54.55 %
- male: 45.45 %
What is the age of people who have Skin ulcer when taking Alkeran? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 9.09 %
- 20-29: 9.09 %
- 30-39: 18.18 %
- 40-49: 18.18 %
- 50-59: 0.0 %
- 60+: 45.45 %
What are other drugs people take besides Alkeran? *
- Velcade: 7 people, 63.64%
- Aredia: 6 people, 54.55%
- Revlimid: 6 people, 54.55%
- Zometa: 6 people, 54.55%
- Lisinopril: 5 people, 45.45%
- Synthroid: 5 people, 45.45%
- Dexamethasone: 5 people, 45.45%
- Cymbalta: 5 people, 45.45%
- Altabax: 5 people, 45.45%
- Coumadin: 4 people, 36.36%
What are other side effects people have besides Skin ulcer? *
- Acute Kidney Failure: 7 people, 63.64%
- Weakness: 7 people, 63.64%
- Exostosis (formation of new bone on the surface of a bone): 6 people, 54.55%
- Constipation: 6 people, 54.55%
- Neuropathy Peripheral (surface nerve damage): 6 people, 54.55%
- Fall: 6 people, 54.55%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 54.55%
- Colitis (inflammation of colon): 6 people, 54.55%
- Diarrhea: 6 people, 54.55%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 6 people, 54.55%
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 2 people, 18.18%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 18.18%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 9.09%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 9.09%
- Infection: 1 person, 9.09%
- Acne (skin problems that cause pimples): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Alkeran and have Skin ulcer?
- Check whether Skin ulcer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Alkeran:
- Alkeran (5,429 reports)
Skin ulcer treatments and more:
- Skin ulcer (33,745 reports)
How severe was Skin ulcer and when was it recovered:
Expand to all the drugs that have ingredients of melphalan:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alkeran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Skin ulcer:
- Skin ulcer (1,452 drugs)
Browse all the conditions that are associated with Skin ulcer:
- Skin ulcer (1,482 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on melphalan (the active ingredients of Alkeran) and Alkeran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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