Allegra allergy and Acute upper airway obstruction - a phase IV clinical study of FDA data

Summary:

Acute upper airway obstruction is reported as a side effect among people who take Allegra allergy (fexofenadine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Xyrem, and have Cataplexy.

The phase IV clinical study analyzes which people have Acute upper airway obstruction when taking Allegra allergy. It is created by eHealthMe based on reports of 13,031 people who have side effects when taking Allegra allergy from the FDA, and is updated regularly.

What is Allegra allergy?

Allegra allergy has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 13,594 Allegra allergy users. Check the latest studies of Allegra allergy.

What is Acute upper airway obstruction?

Acute upper airway obstruction (blockage occurs in the upper airway) is found to be associated with 1,043 drugs and 1,895 conditions by eHealthMe. Check the latest studies of Acute upper airway obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

13,031 people reported to have side effects when taking Allegra allergy.
Among them, 26 people (0.2%) have Acute upper airway obstruction.

Could Allegra allergy cause Acute upper airway obstruction?

Among these 26 people:

How long have people been on Allegra allergy when they have Acute upper airway obstruction? *

What is the gender of people who have Acute upper airway obstruction when taking Allegra allergy? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Acute upper airway obstruction when taking Allegra allergy? *

What are other drugs people take besides Allegra allergy? *

What are other side effects people have besides Acute upper airway obstruction? *

Swallowing Difficulty: 4 people, 15.38%
Rashes (redness): 3 people, 11.54%
Diarrhea: 3 people, 11.54%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 3 people, 11.54%
Cough: 3 people, 11.54%
Ear Discomfort: 3 people, 11.54%
Gait Disturbance: 2 people, 7.69%
Insomnia (sleeplessness): 2 people, 7.69%
Loss Of Consciousness: 2 people, 7.69%
Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night): 2 people, 7.69%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 15.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
Hypersensitivity: 3 people, 11.54%
Sinusitis (inflammation of sinus): 2 people, 7.69%
Multiple Allergies (allergy to multiple agents): 2 people, 7.69%
Renal Cell Carcinoma (a kidney cancer): 2 people, 7.69%
Constipation: 1 person, 3.85%
Anaemia (lack of blood): 1 person, 3.85%
Asthma: 1 person, 3.85%
Bruxism (habitual grinding of the teeth, typically during sleep): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra allergy and have Acute upper airway obstruction?

- Check whether Acute upper airway obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allegra allergy:

Allegra allergy (13,594 reports)

Browse all side effects of Allegra allergy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute upper airway obstruction:

Acute upper airway obstruction (1,043 drugs)

Browse all the conditions that are associated with Acute upper airway obstruction:

Acute upper airway obstruction (1,895 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride (the active ingredients of Allegra allergy) and Allegra allergy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.