Pramipexole dihydrochloride and Sciatica aggravated - a phase IV clinical study of FDA data

Summary:

Sciatica aggravated is reported as a side effect among people who take Pramipexole dihydrochloride (pramipexole dihydrochloride), especially for people who are female, 50-59 old, also take Cymbalta, and have Neuropathy peripheral.

The phase IV clinical study analyzes which people have Sciatica aggravated when taking Pramipexole dihydrochloride. It is created by eHealthMe based on reports of 5,315 people who have side effects when taking Pramipexole dihydrochloride from the FDA, and is updated regularly.

What is Pramipexole dihydrochloride?

Pramipexole dihydrochloride has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 5,671 Pramipexole dihydrochloride users. Check the latest studies of Pramipexole dihydrochloride.

What is Sciatica aggravated?

Sciatica aggravated (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,060 drugs and 403 conditions by eHealthMe. Check the latest studies of Sciatica aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

5,315 people reported to have side effects when taking Pramipexole dihydrochloride.
Among them, 15 people (0.28%) have Sciatica aggravated.

Could Pramipexole dihydrochloride cause Sciatica aggravated?

Among these 15 people:

What is the gender of people who have Sciatica aggravated when taking Pramipexole dihydrochloride? *

female: 73.33 %
male: 26.67 %

What is the age of people who have Sciatica aggravated when taking Pramipexole dihydrochloride? *

What are other drugs people take besides Pramipexole dihydrochloride? *

What are other side effects people have besides Sciatica aggravated? *

Gait Disturbance: 9 people, 60.00%
Joint Pain: 9 people, 60.00%
Fall: 9 people, 60.00%
High Blood Pressure: 9 people, 60.00%
Cough: 9 people, 60.00%
Oedema Peripheral (superficial swelling): 8 people, 53.33%
Chills (felling of cold): 8 people, 53.33%
Heart Rate Increased: 8 people, 53.33%
Insomnia (sleeplessness): 8 people, 53.33%
Nausea (feeling of having an urge to vomit): 8 people, 53.33%

What are the existing conditions these people have? *

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 46.67%
Breast Cancer: 7 people, 46.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 46.67%
Neuropathy Peripheral (surface nerve damage): 7 people, 46.67%
Insomnia (sleeplessness): 2 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Sleep Disorder: 2 people, 13.33%
High Blood Pressure: 1 person, 6.67%
Areflexia (absence of a reflex): 1 person, 6.67%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Pramipexole dihydrochloride and have Sciatica aggravated?

- Check whether Sciatica aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pramipexole dihydrochloride:

Pramipexole dihydrochloride (5,671 reports)

Browse all side effects of Pramipexole dihydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica aggravated:

Sciatica aggravated (1,060 drugs)

Browse all the conditions that are associated with Sciatica aggravated:

Sciatica aggravated (403 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pramipexole dihydrochloride (the active ingredients of Pramipexole dihydrochloride) and Pramipexole dihydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.