Allegra and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Allegra (fexofenadine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Neck pain.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Allegra. It is created by eHealthMe based on reports of 73,095 people who have side effects when taking Allegra from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 655 drugs and 805 conditions by eHealthMe. Check the latest studies of Hypernatraemia.



On Jul, 18, 2026

73,095 people reported to have side effects when taking Allegra.
Among them, 42 people (0.06%) have Hypernatraemia.

Could Allegra cause Hypernatraemia?

Among these 42 people:

How long have people been on Allegra when they have Hypernatraemia? *

  • < 1 month: 75 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypernatraemia when taking Allegra? *

  • female: 45 %
  • male: 55 %

What is the age of people who have Hypernatraemia when taking Allegra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.78 %
  • 30-39: 2.78 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 94.44 %

What are other drugs people take besides Allegra? *

  1. Synthroid: 11 people, 26.19%
  2. Ezetimibe: 10 people, 23.81%
  3. Ondansetron: 10 people, 23.81%
  4. Aspirin: 10 people, 23.81%
  5. Coq10: 10 people, 23.81%
  6. Fish Oil: 10 people, 23.81%
  7. Lipitor: 8 people, 19.05%
  8. Levaquin: 8 people, 19.05%
  9. Zyrtec-D 12 Hour: 7 people, 16.67%
  10. Loratadine: 7 people, 16.67%

What are other side effects people have besides Hypernatraemia? *

  1. Acute Kidney Failure: 19 people, 45.24%
  2. Pneumonia: 17 people, 40.48%
  3. Dehydration (dryness resulting from the removal of water): 15 people, 35.71%
  4. Rashes (redness): 15 people, 35.71%
  5. Fever: 11 people, 26.19%
  6. Pleural Effusion (water on the lungs): 11 people, 26.19%
  7. Abdominal Distension: 11 people, 26.19%
  8. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 10 people, 23.81%
  9. Cellulitis (infection under the skin): 10 people, 23.81%
  10. Caecitis (inflammation of the cecum): 10 people, 23.81%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 10 people, 23.81%
  2. Bleeding Disorders: 10 people, 23.81%
  3. Thrombocytopenia (decrease of platelets in blood): 10 people, 23.81%
  4. Nausea (feeling of having an urge to vomit): 10 people, 23.81%
  5. Nausea And Vomiting: 10 people, 23.81%
  6. Neck Pain: 10 people, 23.81%
  7. Blood Count Abnormal: 7 people, 16.67%
  8. Rashes (redness): 7 people, 16.67%
  9. Sinusitis (inflammation of sinus): 7 people, 16.67%
  10. Nail Tinea (fungal infection of nail): 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allegra:

Hypernatraemia treatments and more:

How severe was Hypernatraemia and when was it recovered:

Expand to all the drugs that have ingredients of fexofenadine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Browse all the conditions that are associated with Hypernatraemia:


How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride (the active ingredients of Allegra) and Allegra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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