Allegra and Skin induration - a phase IV clinical study of FDA data

Summary:

Skin induration is reported as a side effect among people who take Allegra (fexofenadine hydrochloride), especially for people who are female, 60+ old, also take Omniscan, and have Asthma.

The phase IV clinical study analyzes which people have Skin induration when taking Allegra. It is created by eHealthMe based on reports of 73,095 people who have side effects when taking Allegra from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,498 Allegra users. Check the latest studies of Allegra.

What is Skin induration?

Skin induration (an abnormally hard spot or area on the skin) is found to be associated with 519 drugs and 502 conditions by eHealthMe. Check the latest studies of Skin induration.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

73,095 people reported to have side effects when taking Allegra.
Among them, 22 people (0.03%) have Skin induration.

Among these 22 people:

What is the gender of people who have Skin induration when taking Allegra? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Skin induration when taking Allegra? *

What are other drugs people take besides Allegra? *

What are other side effects people have besides Skin induration? *

Skin Tightness: 19 people, 86.36%
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 19 people, 86.36%
Joint Range Of Motion Decreased (disease of joint movement): 17 people, 77.27%
Pain: 17 people, 77.27%
Skin Hypertrophy (skin cells enlarges): 15 people, 68.18%
Oedema Peripheral (superficial swelling): 15 people, 68.18%
Mobility Decreased (ability to move is reduced): 12 people, 54.55%
Joint Contracture (a permanent shortening of a muscle or joint): 10 people, 45.45%
Rashes (redness): 9 people, 40.91%
Hypoaesthesia (reduced sense of touch or sensation): 9 people, 40.91%

What are the existing conditions these people have? *

Asthma: 8 people, 36.36%
Nuclear Magnetic Resonance Imaging Brain: 4 people, 18.18%
Iron Deficiency: 4 people, 18.18%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 9.09%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 9.09%
Itching: 2 people, 9.09%
Thrombocytopenia (decrease of platelets in blood): 1 person, 4.55%
Renal Disorder (kidney disease): 1 person, 4.55%
Pustular Psoriasis (raised bumps on the skin that are filled with pus): 1 person, 4.55%
Hypercoagulation (increased tendency for clotting of the blood): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra and have Skin induration?

- Check whether Skin induration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allegra:

Allegra (75,498 reports)

Skin induration treatments and more:

Skin induration (3,079 reports)

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin induration:

Skin induration (519 drugs)

Browse all the conditions that are associated with Skin induration:

Skin induration (502 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride (the active ingredients of Allegra) and Allegra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.