Allopurinol and Body temperature fluctuation - a phase IV clinical study of FDA data

Summary:

Body temperature fluctuation is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Inflectra, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Body temperature fluctuation when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,869 Allopurinol users. Check the latest studies of Allopurinol.

What is Body temperature fluctuation?

Body temperature fluctuation is found to be associated with 347 drugs and 464 conditions by eHealthMe. Check the latest studies of Body temperature fluctuation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 51 people (0.03%) have Body temperature fluctuation.

Could Allopurinol cause Body temperature fluctuation?

Among these 51 people:

How long have people been on Allopurinol when they have Body temperature fluctuation? *

What is the gender of people who have Body temperature fluctuation when taking Allopurinol? *

female: 7.14 %
male: 92.86 %

What is the age of people who have Body temperature fluctuation when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Body temperature fluctuation? *

Blood Pressure Fluctuation: 19 people, 37.25%
Joint Pain: 18 people, 35.29%
Malaise (a feeling of general discomfort or uneasiness): 17 people, 33.33%
Heart Rate Irregular: 16 people, 31.37%
Weight Decreased: 16 people, 31.37%
Oropharyngeal Pain: 15 people, 29.41%
Pain In Extremity: 15 people, 29.41%
Pain: 14 people, 27.45%
Heart Rate Increased: 14 people, 27.45%
Back Pain: 14 people, 27.45%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 33.33%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 12 people, 23.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 17.65%
Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 13.73%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 11.76%
High Blood Cholesterol: 3 people, 5.88%
Heart Attack: 1 person, 1.96%
Angiopathy (generic term for a disease of the blood vessels): 1 person, 1.96%
Blood Pressure Abnormal: 1 person, 1.96%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Body temperature fluctuation?

- Check whether Body temperature fluctuation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,869 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Body temperature fluctuation:

Body temperature fluctuation (347 drugs)

Browse all the conditions that are associated with Body temperature fluctuation:

Body temperature fluctuation (464 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.