Zicam and Nosebleed - a phase IV clinical study of FDA data

Summary:

Nosebleed is reported as a side effect among people who take Zicam (zinc gluconate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Flonase, and have Nasopharyngitis.

The phase IV clinical study analyzes which people have Nosebleed when taking Zicam. It is created by eHealthMe based on reports of 5,089 people who have side effects when taking Zicam from the FDA, and is updated regularly.

What is Zicam?

Zicam has active ingredients of zinc gluconate. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 5,298 Zicam users. Check the latest studies of Zicam.

What is Nosebleed?

Nosebleed (bleeding from nose) is found to be associated with 2,082 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Nosebleed.

On Apr, 22, 2026

5,089 people reported to have side effects when taking Zicam.
Among them, 35 people (0.69%) have Nosebleed.

Among these 35 people:

How long have people been on Zicam when they have Nosebleed? *

What is the gender of people who have Nosebleed when taking Zicam? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Nosebleed when taking Zicam? *

What are other drugs people take besides Zicam? *

What are other side effects people have besides Nosebleed? *

Smell - Impaired: 19 people, 54.29%
Nasal Discomfort: 10 people, 28.57%
Ageusia (loss of taste functions of the tongue): 6 people, 17.14%
Rhinalgia (pain in the nose): 6 people, 17.14%
Hyposmia (impairment of the sense of smell): 5 people, 14.29%
Rhinorrhea (watery mucus discharge from the nose): 4 people, 11.43%
Nasal Dryness (dry nose): 4 people, 11.43%
Burning Sensation: 4 people, 11.43%
Drug Ineffective: 3 people, 8.57%
Taste - Impaired: 2 people, 5.71%

What are the existing conditions these people have? *

Nasopharyngitis (inflammation of the nasopharynx): 17 people, 48.57%
Rhinovirus Infection: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Zicam and have Nosebleed?

- Check whether Nosebleed is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zicam:

Zicam (5,298 reports)

Nosebleed treatments and more:

Nosebleed (92,075 reports)

Browse all side effects of Zicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nosebleed:

Nosebleed (2,082 drugs)

Browse all the conditions that are associated with Nosebleed:

Nosebleed (3,091 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zinc gluconate (the active ingredients of Zicam) and Zicam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.