Amantadine and Sepsis - a phase IV clinical study of FDA data

Summary:

Sepsis is reported as a side effect among people who take Amantadine (amantadine), especially for people who are male, 60+ old, also take Aspirin, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Sepsis when taking Amantadine. It is created by eHealthMe based on reports of 2,257 people who have side effects when taking Amantadine from the FDA, and is updated regularly.

What is Amantadine?

Amantadine has active ingredients of amantadine. eHealthMe is studying from 2,261 Amantadine users. Check the latest studies of Amantadine.

What is Sepsis?

Sepsis (a severe blood infection that can lead to organ failure and death) is found to be associated with 2,525 drugs and 3,260 conditions by eHealthMe. Check the latest studies of Sepsis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

2,257 people reported to have side effects when taking Amantadine.
Among them, 16 people (0.71%) have Sepsis.

Among these 16 people:

What is the gender of people who have Sepsis when taking Amantadine? *

female: 50 %
male: 50 %

What is the age of people who have Sepsis when taking Amantadine? *

What are other drugs people take besides Amantadine? *

What are other side effects people have besides Sepsis? *

Hallucinations (sensations that appear real but are created by your mind): 6 people, 37.50%
Stress And Anxiety: 6 people, 37.50%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 25.00%
Weakness: 4 people, 25.00%
Fatigue (feeling of tiredness): 4 people, 25.00%
Weight Decreased: 3 people, 18.75%
Urinary Tract Infection: 3 people, 18.75%
Chills (felling of cold): 3 people, 18.75%
High Blood Pressure: 3 people, 18.75%
Memory Loss: 3 people, 18.75%

What are the existing conditions these people have? *

Parkinson's Disease: 6 people, 37.50%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 5 people, 31.25%
Constipation: 3 people, 18.75%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 18.75%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 12.50%
Pain: 2 people, 12.50%
Delusion (a false belief or opinion): 2 people, 12.50%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 12.50%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Amantadine and have Sepsis?

- Check whether Sepsis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amantadine:

Amantadine (2,261 reports)

Sepsis treatments and more:

Sepsis (140,102 reports)

Browse all side effects of Amantadine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sepsis:

Sepsis (2,525 drugs)

Browse all the conditions that are associated with Sepsis:

Sepsis (3,260 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amantadine (the active ingredients of Amantadine) and Amantadine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.